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Albendazole
🥰Excellent
Catalog No. T1152Cas No. 54965-21-8
Alias SKF-62979
Albendazole (SKF-62979) is used as a drug indicated for the treatment of a variety of worm infestations.
Albendazole
🥰Excellent
Purity: 98.76%
Catalog No. T1152Alias SKF-62979Cas No. 54965-21-8
Albendazole (SKF-62979) is used as a drug indicated for the treatment of a variety of worm infestations.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 mg | $38 | In Stock | |
| 100 mg | $48 | In Stock | |
| 500 mg | $56 | In Stock | |
| 1 g | $80 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $39 | In Stock |
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Purity:98.76%
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Product Introduction
Bioactivity
Chemical Properties
| Description | Albendazole (SKF-62979) is used as a drug indicated for the treatment of a variety of worm infestations. |
| In vitro | In sheep lambs administered Albendazole intravenously, the drug and its active metabolite, albendazole sulfoxide, are recovered in tapeworms. In rats, Albendazole significantly increases hepatic activity: it induces a 65-fold increase in CYP1A1-related ethoxyresorufin O-deethylase (EROD) activity, a 6-fold increase in CYP1A2-related methoxyresorufin O-demethylase activity, a 4-fold increase in CYP2B1-related pentoxyresorufin O-dealkylase activity, a 14-fold increase in CYP2B2-related benzyloxyresorufin O-dealkylase activity, and also leads to a partial reduction in CYP2E1-related p-nitrophenol hydroxylase activity. Albendazole is metabolized by liver and lung microsomes in sheep and cattle as well as bovine intestinal microsomes into its pharmacologically active sulfoxide metabolite. |
| In vivo | Albendazole and its sulfoxide metabolites induce the accumulation of cells in the mitotic phase. |
| Synonyms | SKF-62979 |
| Molecular Weight | 265.33 |
| Formula | C12H15N3O2S |
| Cas No. | 54965-21-8 |
| Smiles | N(C(OC)=O)C=1NC=2C(N1)=CC(SCCC)=CC2 |
| Relative Density. | 1.2561 g/cm3 (Estimated) |
Storage & Solubility Information
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 10 mg/mL (37.69 mM), Sonication is recommended.  H2O: < 1 mg/mL (insoluble or slightly soluble) Ethanol: < 1 mg/mL (insoluble or slightly soluble) | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Sci Citations
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
VEGFRVEGFVascular endothelial growth factor receptortapewormSKF62979SKF 62979Reactive Oxygen SpeciesPARPparasiticideParasiteMicrotubuleAssociatedMicrotubule/TubulinMicrotubule AssociatedmicrotubuleLC3InhibitorinhibitHypoxia-inducible factorsHIFsHIFProlylHydroxylaseHIF-PHHIF/HIFProlylHydroxylaseHIF/HIF Prolyl-HydroxylaseHIF/HIF ProlylHydroxylaseHIF Prolyl-HydroxylaseHIF ProlylHydroxylaseHIFEchinococcus granulosuscaspase-3AutophagyApoptosisAntibioticAlbendazole
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