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Imiquimod
🥰Excellent
Catalog No. T0134Cas No. 99011-02-6
Alias S-26308, R 837, IMQ
Imiquimod (R 837) is an immune response modifier and a toll-like receptor 7 (TLR7) agonist with antiviral and antitumor effects. It is used in the study of external genital warts, perianal warts, cancer, and COVID-19, and is commonly employed to induce psoriasis models.
Imiquimod
🥰Excellent
Purity: 99.62%
Catalog No. T0134Alias S-26308, R 837, IMQCas No. 99011-02-6
Imiquimod (R 837) is an immune response modifier and a toll-like receptor 7 (TLR7) agonist with antiviral and antitumor effects. It is used in the study of external genital warts, perianal warts, cancer, and COVID-19, and is commonly employed to induce psoriasis models.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 mg | $37 | In Stock | |
| 100 mg | $50 | In Stock | |
| 200 mg | $68 | In Stock | |
| 500 mg | $113 | In Stock | |
| 1 g | $163 | In Stock |
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Purity:99.62%
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Product Introduction
Bioactivity
Chemical Properties
| Description | Imiquimod (R 837) is an immune response modifier and a toll-like receptor 7 (TLR7) agonist with antiviral and antitumor effects. It is used in the study of external genital warts, perianal warts, cancer, and COVID-19, and is commonly employed to induce psoriasis models. |
| In vivo | In animal models, imiquimod stimulates the innate immune response by increasing NK cell activity, activating macrophages to secrete cytokines and nitric oxide, and inducing proliferation and differentiation of B lymphocytes. Imiquimod stimulates the innate immune response through induction, synthesis, and release of cytokines, including interferon-a (IFN-α), interleukin (IL)-6, and tumour necrosis factor (TNF)-α[1]. |
| Synonyms | S-26308, R 837, IMQ |
| Molecular Weight | 240.30 |
| Formula | C14H16N4 |
| Cas No. | 99011-02-6 |
| Smiles | C(C(C)C)N1C=2C=3C(N=C(N)C2N=C1)=CC=CC3 |
| Relative Density. | 1.28 g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||
| Solubility Information | H2O: Insoluble DMSO: 1.00 mg/mL (4.16 mM), Sonication and heating are recommended.  | ||||||||||
Solution Preparation Table | |||||||||||
DMSO
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
wartsvulvarToll-like Receptor (TLR)TLR8TLR7TLRsquamousSARS-CoVSARSCoVSARS coronavirusS26308S 26308R-837R837papillomavirusnongenitalneoplasiamolluscumkeratosisintraepithelialInhibitorinhibitinfectionImiquimodhumanHSVHerpes simplex virusdiseasecontagiosumcellcarcinomaBowen'sbasal ,cellAutophagyactinic
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