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BRD4 Inhibitor-27

Name: BRD4 Inhibitor-27
Brand: TargetMol
SKU: T78555
Price: 82 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T78555Cas No. 930039-92-2

BRD4 Inhibitor-27 is a potent BRD4 inhibitor that inhibits BRD4 BD1 and BRD4 BD2 with IC50s of 9.6 and 11.3 μM, respectively.BRD4 Inhibitor-27 has anticancer activity and can be used for breast cancer research.

BRD4 Inhibitor-27

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Purity: 99.92%

Catalog No. T78555Cas No. 930039-92-2

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$82	-	In Stock
5 mg	$203	-	In Stock
10 mg	$291	-	In Stock
25 mg	$453	-	In Stock
50 mg	$625	-	In Stock
100 mg	$826	-	In Stock
200 mg	$1,110	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.92%

Appearance:Solid

Color:White

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	BRD4 Inhibitor-27 is a potent BRD4 inhibitor that inhibits BRD4 BD1 and BRD4 BD2 with IC50s of 9.6 and 11.3 μM, respectively.BRD4 Inhibitor-27 has anticancer activity and can be used for breast cancer research.
Targets&IC50	BD1:9.6 uM, BD2:11.3 uM

Chemical Properties

Molecular Weight	346.31
Formula	C₁₆H₁₃F₃N₆
Cas No.	930039-92-2
Smiles	FC(F)(F)C1=NN=C2C=CC(NCCC3=CNC4=C3C=CC=C4)=NN12

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (158.82 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.8876 mL	14.4379 mL	28.8759 mL	144.3793 mL
5 mM	0.5775 mL	2.8876 mL	5.7752 mL	28.8759 mL
10 mM	0.2888 mL	1.4438 mL	2.8876 mL	14.4379 mL
20 mM	0.1444 mL	0.7219 mL	1.4438 mL	7.2190 mL
50 mM	0.0578 mL	0.2888 mL	0.5775 mL	2.8876 mL
100 mM	0.0289 mL	0.1444 mL	0.2888 mL	1.4438 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc