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(S)-(+)-N-3-Benzylnirvanol

Name: (S)-(+)-N-3-Benzylnirvanol
Brand: TargetMol
SKU: T67926
Price: 147 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T67926Cas No. 790676-40-3

Alias ZSN-76403

(S)-(+)-N-3-Benzylnirvanol is a cytochrome P450 CYP2C19 inhibitor with a ki value of 82.5μM for CYP2C9 and 0.25μM for CYP2C19, which can be used to study HIV infection.

(S)-(+)-N-3-Benzylnirvanol

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Purity: 98.90%

Catalog No. T67926Alias ZSN-76403Cas No. 790676-40-3

(S)-(+)-N-3-Benzylnirvanol is a cytochrome P450 CYP2C19 inhibitor with a ki value of 82.5μM for CYP2C9 and 0.25μM for CYP2C19, which can be used to study HIV infection.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$147	In Stock	In Stock
5 mg	$378	In Stock	In Stock
10 mg	$559	In Stock	In Stock
25 mg	$883	In Stock	In Stock
50 mg	$1,190	-	In Stock
100 mg	$1,580	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:98.90%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	(S)-(+)-N-3-Benzylnirvanol is a cytochrome P450 CYP2C19 inhibitor with a ki value of 82.5μM for CYP2C9 and 0.25μM for CYP2C19, which can be used to study HIV infection.
Targets&IC50	CYP2C19:0.53 µM, CYP2C19:< 250 nM(Ki)
In vitro	(S)-(+)-N-3-Benzylnirvanol is a cytochrome P450 CYP2C19 inhibitor with a ki value of 82.5μM for CYP2C9 and 0.25μM for CYP2C19.[1]
Synonyms	ZSN-76403

Chemical Properties

Molecular Weight	294.35
Formula	C₁₈H₁₈N₂O₂
Cas No.	790676-40-3
Smiles	C(C)[C@@]1(C(=O)N(CC2=CC=CC=C2)C(=O)N1)C3=CC=CC=C3
Relative Density.	1.190 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (169.87 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (6.79 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.3973 mL	16.9866 mL	33.9732 mL	169.8658 mL
5 mM	0.6795 mL	3.3973 mL	6.7946 mL	33.9732 mL
10 mM	0.3397 mL	1.6987 mL	3.3973 mL	16.9866 mL
20 mM	0.1699 mL	0.8493 mL	1.6987 mL	8.4933 mL
50 mM	0.0679 mL	0.3397 mL	0.6795 mL	3.3973 mL
100 mM	0.0340 mL	0.1699 mL	0.3397 mL	1.6987 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc