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ZL0590

Name: ZL0590
Brand: TargetMol
SKU: T60072
Price: 68 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T60072Cas No. 2230496-99-6

ZL0590 is an effective and selective inhibitor of BD1-BRD4 (IC50 = 90 nM) with anti-inflammatory activities.

ZL0590

🥰Excellent

Purity: 99.77%

Catalog No. T60072Cas No. 2230496-99-6

ZL0590 is an effective and selective inhibitor of BD1-BRD4 (IC50 = 90 nM) with anti-inflammatory activities.

Pack Size	Price	Availability
1 mg	$68	In Stock
5 mg	$163	In Stock
10 mg	$247	In Stock
25 mg	$446	In Stock
50 mg	$668	In Stock
100 mg	$985	In Stock
1 mL x 10 mM (in DMSO)	$186	In Stock

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Purity:99.77%

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COA LCMS HNMR

Product Introduction

Bioactivity

Description

ZL0590 is an effective and selective inhibitor of BD1-BRD4 (IC50 = 90 nM) with anti-inflammatory activities.

Chemical Properties

Molecular Weight	512.55
Formula	C₂₃H₂₇F₃N₄O₄S
Cas No.	2230496-99-6
Smiles	FC(F)(F)c1ccc(NC(=O)Nc2ccc(cc2)S(=O)(=O)N2CCC[C@H]2CN2CCOCC2)cc1
Relative Density.	1.411 g/cm3 (Predicted)

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 95 mg/mL (185.35 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.9510 mL	9.7551 mL	19.5103 mL	97.5515 mL
5 mM	0.3902 mL	1.9510 mL	3.9021 mL	19.5103 mL
10 mM	0.1951 mL	0.9755 mL	1.9510 mL	9.7551 mL
20 mM	0.0976 mL	0.4878 mL	0.9755 mL	4.8776 mL
50 mM	0.0390 mL	0.1951 mL	0.3902 mL	1.9510 mL
100 mM	0.0195 mL	0.0976 mL	0.1951 mL	0.9755 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc