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Dasantafil

Name: Dasantafil
Brand: TargetMol
SKU: T27122
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T27122Cas No. 569351-91-3

Alias SCH-446132, SCH446132, SCH 446132

Dasantafil (SCH446132) is a small molecule phosphodiesterase-5A (PDE5A) inhibitor used to treat genitourinary disorders and study erectile dysfunction.

Dasantafil

🥰Excellent

Purity: 99.50%

Catalog No. T27122Alias SCH-446132, SCH446132, SCH 446132Cas No. 569351-91-3

Dasantafil (SCH446132) is a small molecule phosphodiesterase-5A (PDE5A) inhibitor used to treat genitourinary disorders and study erectile dysfunction.

Pack Size	Price	Availability	Quantity
2 mg	$29	In Stock

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.50%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Dasantafil (SCH446132) is a small molecule phosphodiesterase-5A (PDE5A) inhibitor used to treat genitourinary disorders and study erectile dysfunction.
Synonyms	SCH-446132, SCH446132, SCH 446132

Chemical Properties

Molecular Weight	522.39
Formula	C₂₂H₂₈BrN₅O₅
Cas No.	569351-91-3
Smiles	C(N1C2=C(N(CCO)C(=O)N(CC)C2=O)N=C1N[C@H]3[C@H](O)CCC3)C4=CC(Br)=C(OC)C=C4
Relative Density.	1.62 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 18.33 mg/mL (35.09 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.9143 mL	9.5714 mL	19.1428 mL	95.7139 mL
5 mM	0.3829 mL	1.9143 mL	3.8286 mL	19.1428 mL
10 mM	0.1914 mL	0.9571 mL	1.9143 mL	9.5714 mL
20 mM	0.0957 mL	0.4786 mL	0.9571 mL	4.7857 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc