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11β-HSD1 inibitor 17

Name: 11β-HSD1 inibitor 17
Brand: TargetMol
SKU: T67903
Price: 109 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T67903Cas No. 946394-50-9

11β-HSD1 inibitor 17 is an inhibitor of 11β-hydroxysteroid dehydrogenase (11β-HSD1).

11β-HSD1 inibitor 17

🥰Excellent

Purity: 99.72%

Catalog No. T67903Cas No. 946394-50-9

11β-HSD1 inibitor 17 is an inhibitor of 11β-hydroxysteroid dehydrogenase (11β-HSD1).

Pack Size	Price	Availability
1 mg	$109	In Stock
5 mg	$270	In Stock
10 mg	$383	In Stock
25 mg	$575	In Stock
50 mg	$777	In Stock
100 mg	$1,050	In Stock
200 mg	$1,370	In Stock

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.72%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description

11β-HSD1 inibitor 17 is an inhibitor of 11β-hydroxysteroid dehydrogenase (11β-HSD1).

Chemical Properties

Molecular Weight	447.47
Formula	C₂₂H₂₀F₃N₃O₂S
Cas No.	946394-50-9
Smiles	C(F)(F)(F)C1=C(N=CC=C1)N2CCN(S(=O)(=O)C3=CC=C(C=C3)C4=CC=CC=C4)CC2
Relative Density.	1.347 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (111.74 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2348 mL	11.1739 mL	22.3479 mL	111.7393 mL
5 mM	0.4470 mL	2.2348 mL	4.4696 mL	22.3479 mL
10 mM	0.2235 mL	1.1174 mL	2.2348 mL	11.1739 mL
20 mM	0.1117 mL	0.5587 mL	1.1174 mL	5.5870 mL
50 mM	0.0447 mL	0.2235 mL	0.4470 mL	2.2348 mL
100 mM	0.0223 mL	0.1117 mL	0.2235 mL	1.1174 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc