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Disulfamide

Name: Disulfamide
Brand: TargetMol
SKU: T60561
Price: 44 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T60561Cas No. 671-88-5

Disulfamide is an orally active carbonic anhydrase inhibitor with an IC50 value of 0.07 μM. Disulfamide has a diuretic effect by inhibiting carbonic anhydrase and preventing the reabsorption of sodium and bicarbonate in the proximal convoluted tubules.

Disulfamide

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Purity: 98.65%

Catalog No. T60561Cas No. 671-88-5

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$44	-	In Stock
5 mg	$109	-	In Stock
10 mg	$167	-	In Stock
25 mg	$326	-	In Stock
50 mg	$445	-	In Stock
100 mg	$601	-	In Stock
200 mg	$812	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:98.65%

Appearance:Solid

Color:White

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Disulfamide is an orally active carbonic anhydrase inhibitor with an IC50 value of 0.07 μM. Disulfamide has a diuretic effect by inhibiting carbonic anhydrase and preventing the reabsorption of sodium and bicarbonate in the proximal convoluted tubules.
Targets&IC50	CA:0.07 μM
In vivo	With a single intraperitoneal injection of 200 mg/kg, disulfamide demonstrates potential blood glucose-raising properties in male Wistar rats[2].

Chemical Properties

Molecular Weight	284.74
Formula	C₇H₉ClN₂O₄S₂
Cas No.	671-88-5
Smiles	S(N)(=O)(=O)C1=CC(S(N)(=O)=O)=C(Cl)C=C1C

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 45 mg/mL (158.04 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.5120 mL	17.5599 mL	35.1198 mL	175.5988 mL
5 mM	0.7024 mL	3.5120 mL	7.0240 mL	35.1198 mL
10 mM	0.3512 mL	1.7560 mL	3.5120 mL	17.5599 mL
20 mM	0.1756 mL	0.8780 mL	1.7560 mL	8.7799 mL
50 mM	0.0702 mL	0.3512 mL	0.7024 mL	3.5120 mL
100 mM	0.0351 mL	0.1756 mL	0.3512 mL	1.7560 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc