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D-Arginine

Name: D-Arginine
Brand: TargetMol
SKU: T41330
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T41330Cas No. 157-06-2

Alias H-D-Arg-OH

D-Arginine is the D-isomer and inactive form of L-Arginine.D-Arginine is an endogenous metabolite and inhibitor of EC 4.1.1.19 (arginine decarboxylase), has broad-spectrum toxicity to microorganisms, and acts as a regulator of microbial subpopulations.

D-Arginine

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Purity: 99.86%

Catalog No. T41330Alias H-D-Arg-OHCas No. 157-06-2

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 g	$29	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.86%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	D-Arginine is the D-isomer and inactive form of L-Arginine.D-Arginine is an endogenous metabolite and inhibitor of EC 4.1.1.19 (arginine decarboxylase), has broad-spectrum toxicity to microorganisms, and acts as a regulator of microbial subpopulations.
In vivo	In male albino mice, D-Arginine was administered via intraperitoneal injection (700–1400 mg/kg; single dose) to evaluate the effects on the central nervous system and toxicity. At 700 mg/kg, D-Arginine exhibited central excitatory effects, while at 1400 mg/kg, D-Arginine produced central depressant effects, including prolonged barbiturate-induced sleep and significant anticonvulsant activity against pentylenetetrazole-induced seizures. The LD₅₀ was determined to be 2800 mg/kg, and pretreatment with propranolol (2 mg/kg) or betamethasone (0.5 mg/kg) increased the LD₅₀ to 3600 mg/kg and 3300 mg/kg, respectively. [1]
Synonyms	H-D-Arg-OH

Chemical Properties

Molecular Weight	174.2
Formula	C₆H₁₄N₄O₂
Cas No.	157-06-2
Smiles	C(CCNC(=N)N)[C@H](C(O)=O)N
Relative Density.	1.2297 g/cm3 (Estimated)
Sequence	H-D-Arg-OH
Sequence Short	R

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 20 mg/mL (114.81 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	5.7405 mL	28.7026 mL	57.4053 mL	287.0264 mL
5 mM	1.1481 mL	5.7405 mL	11.4811 mL	57.4053 mL
10 mM	0.5741 mL	2.8703 mL	5.7405 mL	28.7026 mL
20 mM	0.2870 mL	1.4351 mL	2.8703 mL	14.3513 mL
50 mM	0.1148 mL	0.5741 mL	1.1481 mL	5.7405 mL
100 mM	0.0574 mL	0.2870 mL	0.5741 mL	2.8703 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc