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ADS032

Name: ADS032
Brand: TargetMol
SKU: T79906
Price: 42 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T79906Cas No. 2757333-37-0

Alias BT-032

ADS032 (BT-032) is an NLRP1 and NLRP3 inhibitor with anti-inflammatory activity,, inhibits the activation of NLRP1 and NLRP3, inhibits Nigericin-induced IL-1β production, and can be used to study respiratory inflammation or infection.

ADS032

🥰Excellent

Purity: 98.37%

Catalog No. T79906Alias BT-032Cas No. 2757333-37-0

Pack Size	Price	Availability
1 mg	$42	In Stock
5 mg	$98	In Stock
10 mg	$168	In Stock
25 mg	$338	In Stock
50 mg	$579	In Stock
100 mg	$928	In Stock
1 mL x 10 mM (in DMSO)	$108	In Stock

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:98.37%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	ADS032 (BT-032) is an NLRP1 and NLRP3 inhibitor with anti-inflammatory activity,, inhibits the activation of NLRP1 and NLRP3, inhibits Nigericin-induced IL-1β production, and can be used to study respiratory inflammation or infection.
Synonyms	BT-032

Chemical Properties

Molecular Weight	403.54
Formula	C₂₂H₂₉NO₄S
Cas No.	2757333-37-0
Smiles	O=C(O)CCCC1=CC=C(C=C1)C=2C=CC(=CC2)S(=O)(=O)N(CCC)CCC

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Ethanol: 5 mg/mL (12.39 mM), Sonication and heating are recommended.

DMSO: 80 mg/mL (198.25 mM), Sonication is recommended.

Solution Preparation Table

Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4781 mL	12.3903 mL	24.7807 mL	123.9035 mL
5 mM	0.4956 mL	2.4781 mL	4.9561 mL	24.7807 mL
10 mM	0.2478 mL	1.2390 mL	2.4781 mL	12.3903 mL

DMSO

	1mg	5mg	10mg	50mg
20 mM	0.1239 mL	0.6195 mL	1.2390 mL	6.1952 mL
50 mM	0.0496 mL	0.2478 mL	0.4956 mL	2.4781 mL
100 mM	0.0248 mL	0.1239 mL	0.2478 mL	1.2390 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc