Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CDK7-IN-6 is a highly effective and specific inhibitor (IC50 ≤100 nM) of cyclin-dependent kinase 7 (CDK7). It showcases remarkable selectivity, with more than a 200-fold preference for CDK7 over CDK1, CDK2, and CDK5. This compound holds significant potential for cancer research purposes.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | Inquiry | $ 970.00 |
Description | CDK7-IN-6 is a highly effective and specific inhibitor (IC50 ≤100 nM) of cyclin-dependent kinase 7 (CDK7). It showcases remarkable selectivity, with more than a 200-fold preference for CDK7 over CDK1, CDK2, and CDK5. This compound holds significant potential for cancer research purposes. |
Targets&IC50 | CDK7:≤100 nM (IC50) |
In vitro | CDK7-IN-6 effectively suppresses cell viability in various cancer cell lines, including HCT116, H460, MV4-11, A2780, and OVCAR cells, demonstrating potent inhibition (IC50 ≤1 μM)[1]. |
Synonyms | CDK7-IN-6 |
Molecular Weight | 524.07 |
Formula | C26H34ClN9O |
CAS No. | 2378710-04-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
CDK7-IN-6 2378710-04-2 CDK7IN6 CDK-7-IN-6 CDK7 IN 6 inhibitor inhibit