Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AChE/BChE-IN-10 is a potent dual inhibitor of AChE and BChE with IC50 values of 0.176, and 0.47 μM, respectively. AChE/BChE-IN-10 exhibits good blood brain barrier permeability. AChE/BChE-IN-10 can inhibit Aβ-aggregation.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 68.00 | |
10 mg | In stock | $ 109.00 | |
25 mg | In stock | $ 228.00 | |
50 mg | In stock | $ 372.00 | |
100 mg | In stock | $ 539.00 | |
500 mg | In stock | $ 1,170.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 84.00 |
Description | AChE/BChE-IN-10 is a potent dual inhibitor of AChE and BChE with IC50 values of 0.176, and 0.47 μM, respectively. AChE/BChE-IN-10 exhibits good blood brain barrier permeability. AChE/BChE-IN-10 can inhibit Aβ-aggregation. |
Targets&IC50 | AChE:0.176 μM, BChE:0.47 μM |
In vitro | AChE/BChE-IN-10 inhibits AChE in a non-competitive manner (Ki= 0.21 μM), and BChE in a mixed-fashion(Ki= 0.15 μM)[1]. |
Molecular Weight | 402.53 |
Formula | C26H30N2O2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 4.03 mg/mL (10 mM)
You can also refer to dose conversion for different animals. More
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AChE/BChE-IN-10 Neuroscience AChR AChE inhibitor inhibit