Shopping Cart

Remove All

Your shopping cart is currently empty

Proceed to checkout Continue shopping

AK-778-XXMU

Name: AK-778-XXMU
Brand: TargetMol
SKU: T61802
Rating: 4.5 (1 reviews)

😃Good

Catalog No. T61802Cas No. 1227045-76-2

AK-778-XXMU is an ID2 antagonist with a KD value of 129 nM.AK-778-XXMU has potential antitumor and anticancer activity and can be used for the study of gliomas.

AK-778-XXMU

😃Good

Catalog No. T61802Cas No. 1227045-76-2

AK-778-XXMU is an ID2 antagonist with a KD value of 129 nM.AK-778-XXMU has potential antitumor and anticancer activity and can be used for the study of gliomas.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 mg	$49	7-10 days	7-10 days
1 mL x 10 mM (in DMSO)	$92	7-10 days	7-10 days

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:>99.99%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description

AK-778-XXMU is an ID2 antagonist with a KD value of 129 nM.AK-778-XXMU has potential antitumor and anticancer activity and can be used for the study of gliomas.

Chemical Properties

Molecular Weight	392.835
Formula	C₂₂H₁₇ClN₂O₃
Cas No.	1227045-76-2
Smiles	O=C(C1=NC=CC=C1)CC2(O)C(=O)N(C=3C=CC=CC32)CC=4C=CC=C(Cl)C4

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (203.65 mM), Sonification is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.5456 mL	12.7280 mL	25.4560 mL	127.2799 mL
5 mM	0.5091 mL	2.5456 mL	5.0912 mL	25.4560 mL
10 mM	0.2546 mL	1.2728 mL	2.5456 mL	12.7280 mL
20 mM	0.1273 mL	0.6364 mL	1.2728 mL	6.3640 mL
50 mM	0.0509 mL	0.2546 mL	0.5091 mL	2.5456 mL
100 mM	0.0255 mL	0.1273 mL	0.2546 mL	1.2728 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc