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KHS101 hydrochloride

Name: KHS101 hydrochloride
Brand: TargetMol
SKU: T5170
Price: 31 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T5170Cas No. 1784282-12-7

KHS101 is a TACC3 inhibitor and can selectively induce a neuronal differentiation phenotype.

KHS101 hydrochloride

🥰Excellent

Purity: 99.6%

Catalog No. T5170Cas No. 1784282-12-7

KHS101 is a TACC3 inhibitor and can selectively induce a neuronal differentiation phenotype.

Pack Size	Price	Availability
2 mg	$31	In Stock
5 mg	$50	In Stock
10 mg	$77	In Stock
25 mg	$158	In Stock
50 mg	$265	In Stock
100 mg	$389	In Stock
200 mg	$553	In Stock
1 mL x 10 mM (in DMSO)	$56	In Stock

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Batch Information

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Purity:99.6%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description

KHS101 is a TACC3 inhibitor and can selectively induce a neuronal differentiation phenotype.

Chemical Properties

Molecular Weight	375.92
Formula	C₁₈H₂₂ClN₅S
Cas No.	1784282-12-7
Smiles	Cl.CC(C)CNc1ccnc(NCc2csc(n2)-c2ccccc2)n1
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Ethanol: 50 mg/mL (133.01 mM), Sonication is recommended.

DMSO: 50 mg/mL (133.01 mM), Sonication is recommended.

Solution Preparation Table

Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6601 mL	13.3007 mL	26.6014 mL	133.0070 mL
5 mM	0.5320 mL	2.6601 mL	5.3203 mL	26.6014 mL
10 mM	0.2660 mL	1.3301 mL	2.6601 mL	13.3007 mL
20 mM	0.1330 mL	0.6650 mL	1.3301 mL	6.6504 mL
50 mM	0.0532 mL	0.2660 mL	0.5320 mL	2.6601 mL
100 mM	0.0266 mL	0.1330 mL	0.2660 mL	1.3301 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc