Powder: -20°C for 3 years | In solvent: -80°C for 1 year
TTBK1-IN-2 (N-[4-(4-chlorophenoxy)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine) is an inhibitor of Tau-Tubulin kinase (TTBK1) with IC50s of 0.24 and 4.22 µM. TTBK1-IN-2 reduces TDP-43 phosphorylation both in cell cultures and the spinal cord of transgenic TDP-43 mice.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 123.00 | |
5 mg | In stock | $ 285.00 | |
10 mg | In stock | $ 420.00 | |
25 mg | In stock | $ 698.00 | |
50 mg | In stock | $ 993.00 | |
100 mg | In stock | $ 1,330.00 | |
500 mg | In stock | $ 2,680.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 298.00 |
Description | TTBK1-IN-2 (N-[4-(4-chlorophenoxy)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine) is an inhibitor of Tau-Tubulin kinase (TTBK1) with IC50s of 0.24 and 4.22 µM. TTBK1-IN-2 reduces TDP-43 phosphorylation both in cell cultures and the spinal cord of transgenic TDP-43 mice. |
Synonyms | N-[4-(4-chlorophenoxy)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine |
Molecular Weight | 336.77 |
Formula | C18H13ClN4O |
CAS No. | 2765453-51-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 45 mg/mL (133.62 mM), when pH is adjusted to 2 with HCl. Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
TTBK1-IN-2 2765453-51-6 Cytoskeletal Signaling Microtubule Associated N-[4-(4-chlorophenoxy)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine inhibitor inhibit