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2'-Deoxyguanosine monohydrate

Name: 2'-Deoxyguanosine monohydrate
Brand: TargetMol
SKU: T4715
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T4715Cas No. 312693-72-4

Alias Guanine-2'-deoxyriboside

2'-Deoxyguanosine monohydrate (Guanine-2'-deoxyriboside) is a nucleoside consisting of the base guanine and the sugar deoxyribose. It is like guanosine, but with one oxygen atom removed. It is a nucleoside component of DNA. 2'-Deoxyguanosine monohydrate can be converted to 8-hydroxy-deoxyguanosine (8-OHdG) due to hydroxyl radical attack at the C8 of guanine. 8-OHdG is a sensitive marker of the DNA damage This damage, if left unrepaired, has been proposed to contribute to mutagenicity and cancer promotion.

2'-Deoxyguanosine monohydrate

🥰Excellent

Purity: 99.73%

Catalog No. T4715Alias Guanine-2'-deoxyribosideCas No. 312693-72-4

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 g	$33	-	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Purity:99.73%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description

Synonyms

Guanine-2'-deoxyriboside

Chemical Properties

Molecular Weight	285.26
Formula	C₁₀H₁₅N₅O₅
Cas No.	312693-72-4
Smiles	O.Nc1nc2n(cnc2c(=O)[nH]1)[C@H]1C[C@H](O)[C@@H](CO)O1
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (350.5 mM), Sonication is recommended.

1 M NH4OH: 50 mg/mL (175.28 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (11.57 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

1 M NH4OH/DMSO

	1mg	5mg	10mg	50mg
1 mM	3.5056 mL	17.5279 mL	35.0557 mL	175.2787 mL
5 mM	0.7011 mL	3.5056 mL	7.0111 mL	35.0557 mL
10 mM	0.3506 mL	1.7528 mL	3.5056 mL	17.5279 mL
20 mM	0.1753 mL	0.8764 mL	1.7528 mL	8.7639 mL
50 mM	0.0701 mL	0.3506 mL	0.7011 mL	3.5056 mL
100 mM	0.0351 mL	0.1753 mL	0.3506 mL	1.7528 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc