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SDZ-MKS 492

Name: SDZ-MKS 492
Brand: TargetMol
SKU: T12873
Rating: 4.5 (1 reviews)

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Catalog No. T12873Cas No. 114606-56-3

Alias MKS 492

SDZ-MKS 492 is a selective type III isozyme cyclic nucleotide phosphodiesterase inhibitor.

SDZ-MKS 492

😃Good

Catalog No. T12873Alias MKS 492Cas No. 114606-56-3

SDZ-MKS 492 is a selective type III isozyme cyclic nucleotide phosphodiesterase inhibitor.

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$297	6-8 weeks	6-8 weeks
25 mg	$987	6-8 weeks	6-8 weeks
50 mg	$1,360	6-8 weeks	6-8 weeks
100 mg	$1,860	6-8 weeks	6-8 weeks
1 mL x 10 mM (in DMSO)	$365	6-8 weeks	6-8 weeks

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description	SDZ-MKS 492 is a selective type III isozyme cyclic nucleotide phosphodiesterase inhibitor.
Synonyms	MKS 492

Chemical Properties

Molecular Weight	433.46
Formula	C₂₀H₂₇N₅O₆
Cas No.	114606-56-3
Relative Density.	1.36 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 250 mg/mL (576.75 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3070 mL	11.5351 mL	23.0702 mL	115.3509 mL
5 mM	0.4614 mL	2.3070 mL	4.6140 mL	23.0702 mL
10 mM	0.2307 mL	1.1535 mL	2.3070 mL	11.5351 mL
20 mM	0.1154 mL	0.5768 mL	1.1535 mL	5.7675 mL
50 mM	0.0461 mL	0.2307 mL	0.4614 mL	2.3070 mL
100 mM	0.0231 mL	0.1154 mL	0.2307 mL	1.1535 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc