Powder: -20°C for 3 years | In solvent: -80°C for 1 year
EGFR-IN-71 is a potent inhibitor of epidermal growth factor receptor (EGFR) (IC50= 3.7 μM). EGFR-IN-71 has research value in chordoma.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 8-10 weeks | $ 1,520.00 | |
50 mg | 8-10 weeks | $ 1,980.00 | |
100 mg | 8-10 weeks | $ 2,500.00 |
Description | EGFR-IN-71 is a potent inhibitor of epidermal growth factor receptor (EGFR) (IC50= 3.7 μM). EGFR-IN-71 has research value in chordoma. |
In vitro | EGFR-IN-71 (also known as compound 41) demonstrated inhibitory effects on various chordoma cell lines including U-CH1, U-CH2, CH22, UM-Chor1, U-CH12, and U-CH7 when tested at concentrations ranging from 0-100 μM over a period of 72 hours. This activity was quantitatively assessed using a Cell Viability Assay, which revealed that the compound effectively reduced the viability of these cell lines with half-maximal inhibitory concentration (IC50) values of 9.1 μM, 16 μM, 0.48 μM, 25 μM, 0.96 μM, and 8.0 μM, respectively. |
Molecular Weight | 405.62 |
Formula | C16H9ClIN3 |
CAS No. | 2676155-98-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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EGFR-IN-71 2676155-98-7 inhibitor inhibit