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Vindesine sulfate

🥰Excellent
Catalog No. T22455Cas No. 59917-39-4
Alias VDS, DVA, Desacetylvinblastine amide, Desacetyl Vinblastine amide, DAVA

Vindesine sulfate (Desacetyl Vinblastine amide) is a vinca alkaloid which is a synthetic derivative of vinblastine, binds to the microtubular proteins of the mitotic spindle, leading to crystallization of the microtubule and mitotic arrest or cell death.

Vindesine sulfate
Other Forms of Vindesine sulfate:
VindesineTN229953643-48-4
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Vindesine sulfate

🥰Excellent
Purity: 97.51%
Catalog No. T22455Alias VDS, DVA, Desacetylvinblastine amide, Desacetyl Vinblastine amide, DAVACas No. 59917-39-4
Vindesine sulfate (Desacetyl Vinblastine amide) is a vinca alkaloid which is a synthetic derivative of vinblastine, binds to the microtubular proteins of the mitotic spindle, leading to crystallization of the microtubule and mitotic arrest or cell death.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$82In StockIn Stock
20 mg$207In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:97.51%
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COA HNMR LCMS

Product Introduction

Bioactivity
Description
Vindesine sulfate (Desacetyl Vinblastine amide) is a vinca alkaloid which is a synthetic derivative of vinblastine, binds to the microtubular proteins of the mitotic spindle, leading to crystallization of the microtubule and mitotic arrest or cell death.
SynonymsVDS, DVA, Desacetylvinblastine amide, Desacetyl Vinblastine amide, DAVA
Chemical Properties
Molecular Weight852
FormulaC43H57N5O11S
Cas No.59917-39-4
SmilesOS(O)(=O)=O.[H][C@@]12N3CC[C@@]11c4cc(c(OC)cc4N(C)[C@@]1([H])[C@](O)([C@H](O)[C@]2(CC)C=CC3)C(N)=O)[C@]1(C[C@]2([H])CN(C[C@](O)(CC)C2)CCc2c1[nH]c1ccccc21)C(=O)OC
Relative Density.1.41 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 8.52 mg/mL (10 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween-80+45% Saline: 0.5 mg/mL (0.59 mM), Sonication is recommeded.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.1737 mL5.8685 mL11.7371 mL58.6854 mL
5 mM0.2347 mL1.1737 mL2.3474 mL11.7371 mL
10 mM0.1174 mL0.5869 mL1.1737 mL5.8685 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Vindesine SulfateVindesine sulfateVindesineMicrotubule/TubulinL-cellsInhibitorinhibitDesacetylvinblastine AmideDesacetyl Vinblastine AmideB16 cellsantitumoranti-proliferation
Related Tags: buy Vindesine sulfate | purchase Vindesine sulfate | Vindesine sulfate cost | order Vindesine sulfate | Vindesine sulfate chemical structure | Vindesine sulfate formula | Vindesine sulfate molecular weight
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