Powder: -20°C for 3 years | In solvent: -80°C for 1 year
LY3372689 (Formulaic Ia) is an orally active O-GlcNAcase (OGA) enzyme inhibitor for tau protein-based disorders including Alzheimer's disease.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 129.00 | |
5 mg | In stock | $ 322.00 | |
10 mg | In stock | $ 517.00 | |
25 mg | In stock | $ 838.00 | |
50 mg | In stock | $ 1,160.00 | |
100 mg | In stock | $ 1,560.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 343.00 |
Description | LY3372689 (Formulaic Ia) is an orally active O-GlcNAcase (OGA) enzyme inhibitor for tau protein-based disorders including Alzheimer's disease. |
In vivo | In rat studies, LY3372689 demonstrated a dose-dependent change in OGA EO following a single oral dose with a maximum EO of greater than 90%. A plasma concentration-dependent increase in brain OGA EO was observed with EO exceeding 90% at 24 hours following the highest dose of LY3372689 administered.[1] |
Synonyms | Formulaic Ia |
Molecular Weight | 383.44 |
Formula | C16H22FN5O3S |
CAS No. | 2241514-56-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 225.0 mg/mL (586.8 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
LY3372689 2241514-56-5 Cytoskeletal Signaling Microtubule Associated LY 3372689 Formulaic Ia LY-3372689 inhibitor inhibit