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Shanziside

🥰Excellent
Catalog No. TN1110Cas No. 29836-27-9
Alias Shanzhiside

Shanziside (Shanzhiside) has immunosuppressive activity, it shows significant inhibition of IL-2 secretion by phorbol myristate acetate and anti-CD28 monoclonal antibody co-stimulated activation of human peripheral blood T cells.

Shanziside

Shanziside

🥰Excellent
Purity: 99.83%
Catalog No. TN1110Alias ShanzhisideCas No. 29836-27-9
Shanziside (Shanzhiside) has immunosuppressive activity, it shows significant inhibition of IL-2 secretion by phorbol myristate acetate and anti-CD28 monoclonal antibody co-stimulated activation of human peripheral blood T cells.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$70In StockIn Stock
5 mg$163In StockIn Stock
10 mg$240In StockIn Stock
25 mg$453In StockIn Stock
50 mg$668In StockIn Stock
1 mL x 10 mM (in DMSO)$180In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.83%
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COA HNMR HPLC

Product Introduction

Bioactivity
Description
Shanziside (Shanzhiside) has immunosuppressive activity, it shows significant inhibition of IL-2 secretion by phorbol myristate acetate and anti-CD28 monoclonal antibody co-stimulated activation of human peripheral blood T cells.
In vitro
A new iridoid, gardaloside (1), and a new safranal-type monoterpene, jasminoside G (2), together with 10 known compounds including nine iridoids and a second safranal-type monoterpene, were isolated from the fruits of Gardenia jasminoides. The structures of 1 and 2 were established on the basis of spectroscopic evidence.
SynonymsShanzhiside
Chemical Properties
Molecular Weight392.36
FormulaC16H24O11
Cas No.29836-27-9
Smiles[H][C@]12[C@H](O)C[C@](C)(O)[C@@]1([H])[C@H](O[C@]1([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)OC=C2C(O)=O
Relative Density.1.69 g/cm3 (Predicted)
Storage & Solubility Information
Storagekeep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 45 mg/mL (114.69 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 1 mg/mL (2.55 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.5487 mL12.7434 mL25.4868 mL127.4340 mL
5 mM0.5097 mL2.5487 mL5.0974 mL25.4868 mL
10 mM0.2549 mL1.2743 mL2.5487 mL12.7434 mL
20 mM0.1274 mL0.6372 mL1.2743 mL6.3717 mL
50 mM0.0510 mL0.2549 mL0.5097 mL2.5487 mL
100 mM0.0255 mL0.1274 mL0.2549 mL1.2743 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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%
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

ShanzisideIridoidInhibitorinhibitILReceptorIL Receptorglucoside
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