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RY785

🥰Excellent
Catalog No. T12786Cas No. 1393748-80-5

RY785 is a potent and selective inhibitor of voltage-gated potassium channels, such as KV2.2 (IC50 = 50 nM). This compound may be used in pain relief studies.

RY785
Other Forms of RY785:
Kv2-IN-A1T8977689297-68-5
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RY785

🥰Excellent
Purity: 99.78%
Catalog No. T12786Cas No. 1393748-80-5
RY785 is a potent and selective inhibitor of voltage-gated potassium channels, such as KV2.2 (IC50 = 50 nM). This compound may be used in pain relief studies.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$47In StockIn Stock
5 mg$147In StockIn Stock
10 mg$247In StockIn Stock
25 mg$419In StockIn Stock
50 mg$589In StockIn Stock
100 mg$828In StockIn Stock
200 mg$1,150In StockIn Stock
1 mL x 10 mM (in DMSO)$127In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:99.78%
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COA HNMR LCMS

Product Introduction

Bioactivity
Description
RY785 is a potent and selective inhibitor of voltage-gated potassium channels, such as KV2.2 (IC50 = 50 nM). This compound may be used in pain relief studies.
Targets&IC50
Kv2.2 channel:50 nM
Chemical Properties
Molecular Weight392.47
FormulaC21H20N4O2S
Cas No.1393748-80-5
SmilesCOc1cccc(CC(C)C(=O)Nc2ccc3nc([nH]c3c2)-c2cscn2)c1
Relative Density.1.333 g/cm3 (Predicted)
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 60 mg/mL (152.88 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.5480 mL12.7398 mL25.4797 mL127.3983 mL
5 mM0.5096 mL2.5480 mL5.0959 mL25.4797 mL
10 mM0.2548 mL1.2740 mL2.5480 mL12.7398 mL
20 mM0.1274 mL0.6370 mL1.2740 mL6.3699 mL
50 mM0.0510 mL0.2548 mL0.5096 mL2.5480 mL
100 mM0.0255 mL0.1274 mL0.2548 mL1.2740 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

voltage-gated potassium (KV2) channelSodium ChannelRY-785RY785RY 785PotassiumChannelPotassium ChannelNa+ channelsNa channelsKv2.2Inhibitorinhibit
Related Tags: buy RY785 | purchase RY785 | RY785 cost | order RY785 | RY785 chemical structure | RY785 formula | RY785 molecular weight
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