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Aureobasidin A

Name: Aureobasidin A
Brand: TargetMol
SKU: T9267
Price: 122 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T9267Cas No. 127785-64-2

Aureobasidin A is a cyclic peptide and an antifungal antibiotic. Aureobasidin A is an inhibitor of the inositolphosphorylceramide synthase AUR1.

Aureobasidin A

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Purity: 98.57%

Catalog No. T9267Cas No. 127785-64-2

Aureobasidin A is a cyclic peptide and an antifungal antibiotic. Aureobasidin A is an inhibitor of the inositolphosphorylceramide synthase AUR1.

Pack Size	Price	Availability
1 mg	$122	In Stock
5 mg	$263	In Stock
10 mg	$396	In Stock
25 mg	$648	In Stock
50 mg	$912	In Stock
100 mg	$1,220	In Stock
200 mg	$1,650	In Stock
1 mL x 10 mM (in DMSO)	$469	In Stock

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Batch Information

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Purity:98.57%

Resource Download

COA LCMS HNMR MS

Product Introduction

Bioactivity

Description	Aureobasidin A is a cyclic peptide and an antifungal antibiotic. Aureobasidin A is an inhibitor of the inositolphosphorylceramide synthase AUR1.
In vitro	Ureobasidin A is a cyclicdepsipeptide antifungal produced by Aureobasidium pullulans with a strong fungicidal activity against a variety of fungi, including Candida[1].

Chemical Properties

Molecular Weight	1101.42
Formula	C₆₀H₉₂N₈O₁₁
Cas No.	127785-64-2
Smiles	[H][C@@]12CCCN1C(=O)[C@H](Cc1ccccc1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C(C)C)N(C)C(=O)[C@]([H])(OC(=O)[C@@H](N(C)C(=O)[C@H](CC(C)C)NC(=O)[C@H](C(C)C)N(C)C(=O)[C@@]([H])(NC2=O)[C@H](C)CC)C(C)(C)O)[C@H](C)CC
Relative Density.	1.19 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (49.94 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	0.9079 mL	4.5396 mL	9.0792 mL	45.3959 mL
5 mM	0.1816 mL	0.9079 mL	1.8158 mL	9.0792 mL
10 mM	0.0908 mL	0.4540 mL	0.9079 mL	4.5396 mL
20 mM	0.0454 mL	0.2270 mL	0.4540 mL	2.2698 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc