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NT-0796

Name: NT-0796
Brand: TargetMol
SKU: T81637
Price: 197 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T81637Cas No. 2272917-13-0

Alias NT0796, NT 0796

NT-0796 is a brain-permeable, potent, and selective inhibitor of the inflammasome NLRP3, inhibiting NLRP3 activation.NT-0796 is a potential NDT-19795 delivery vector.

NT-0796

🥰Excellent

Purity: 99.67%

Catalog No. T81637Alias NT0796, NT 0796Cas No. 2272917-13-0

NT-0796 is a brain-permeable, potent, and selective inhibitor of the inflammasome NLRP3, inhibiting NLRP3 activation.NT-0796 is a potential NDT-19795 delivery vector.

Pack Size	Price	Availability
1 mg	$197	In Stock
5 mg	$496	In Stock
10 mg	$793	In Stock
25 mg	$1,180	In Stock
50 mg	$1,630	In Stock
100 mg	$2,190	In Stock

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.67%

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COA HPLC HNMR

Product Introduction

Bioactivity

Description	NT-0796 is a brain-permeable, potent, and selective inhibitor of the inflammasome NLRP3, inhibiting NLRP3 activation.NT-0796 is a potential NDT-19795 delivery vector.
Synonyms	NT0796, NT 0796

Chemical Properties

Molecular Weight	409.48
Formula	C₂₃H₂₇N₃O₄
Cas No.	2272917-13-0
Smiles	N(C(O[C@H](CC=1N=CC=CN1)C(OC(C)C)=O)=O)C2=C3C(=CC4=C2CCC4)CCC3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (195.37 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4421 mL	12.2106 mL	24.4212 mL	122.1061 mL
5 mM	0.4884 mL	2.4421 mL	4.8842 mL	24.4212 mL
10 mM	0.2442 mL	1.2211 mL	2.4421 mL	12.2106 mL
20 mM	0.1221 mL	0.6105 mL	1.2211 mL	6.1053 mL
50 mM	0.0488 mL	0.2442 mL	0.4884 mL	2.4421 mL
100 mM	0.0244 mL	0.1221 mL	0.2442 mL	1.2211 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc