Powder: -20°C for 3 years | In solvent: -80°C for 1 year
NT-0796, a selective CNS-penetrant NLRP3 inflammasome inhibitor, exhibits potent inhibitory activity with an IC50 of 0.32 nM in PBMC assays. As an isopropyl ester, it is metabolized intracellularly into NDT-19795, its active carboxylic acid form. This compound shows promise for research into neuroinflammatory diseases [1].
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Description | NT-0796, a selective CNS-penetrant NLRP3 inflammasome inhibitor, exhibits potent inhibitory activity with an IC50 of 0.32 nM in PBMC assays. As an isopropyl ester, it is metabolized intracellularly into NDT-19795, its active carboxylic acid form. This compound shows promise for research into neuroinflammatory diseases [1]. |
Molecular Weight | 409.48 |
Formula | C23H27N3O4 |
CAS No. | 2272917-13-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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NT-0796 2272917-13-0 Immunology/Inflammation NOD-like Receptor (NLR) inhibitor inhibit