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Fluorescein Sodium

Name: Fluorescein Sodium
Brand: TargetMol
SKU: T4065
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: VST-1001, VST1001, VST 1001, Fluorescite, Acid yellow 73) Copy Product Info

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Synonyms: VST-1001, VST1001, VST 1001, Fluorescite, Acid yellow 73

Catalog No. T4065 Copy Product Info

Purity: 97.05%

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Fluorescein Sodium (VST-1001) is a phthalic indicator dye. It is used therapeutically as a diagnostic aid in corneal injuries and corneal trauma.

Cas No. 518-47-8

Pack Size	Price	USA Stock	Global Stock
200 mg	$30	In Stock	In Stock
500 mg	$40	In Stock	In Stock
1 g	$57	In Stock	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:97.05%

Appearance:Solid

Color:Red

Resource Download

COA LCMS HNMR

Product Introduction

Fluorescein Sodium AI Summary

Fluorescein Sodium exhibits bioactivities related to inhibiting human tyrosyl-DNA phosphodiesterase 1 and blocking cell entry of Lassa Virus, Marburg Virus, and Ebola Virus through various mechanisms. The compound demonstrates different potencies in these assays, suggesting its potential as a multi-target bioactive agent against these viral infections. It also shows an apparent permeability (Papp) of 2.72 ucm/s from the apical to basolateral side in Caco2 cells at concentrations of 1 to 10 uM over 90 minutes, indicating good potential bioavailability. Additionally, Fluorescein Sodium inhibits N-terminal 31 residues truncated FTO demethylase activity using m6A containing ssRNA as a substrate, with an IC50 of 3650.0 nM after a 1-hour incubation based on LC-MS analysis..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Fluorescein Sodium (VST-1001) is a phthalic indicator dye. It is used therapeutically as a diagnostic aid in corneal injuries and corneal trauma.
Synonyms	VST-1001, VST1001, VST 1001, Fluorescite, Acid yellow 73
Animal Research	Fluorescein Sodium live tissue imaging I. Solution preparation Preparation of mother solution and working solution: 0.01-0.1 g of fluorescein sodium powder is placed in a light-proof test tube, and 10 mL of saline is added to prepare a 1-10% fluorescein sodium solution. After fully dissolving, it is used as a working solution. II. Operation steps Mouse kidney staining 1. The mouse is anesthetized by intraperitoneal injection of 1% sodium pentobarbital, and the kidney is completely removed during surgery. 2. Use forceps and scissors to remove the kidney surface membrane, apply fluorescein sodium to the kidney surface for 2 minutes, and then wash it three times with saline. 3. Apply 1% methylene blue staining solution to the surface for 2 minutes, wash it three times with saline after the time is up, and then observe it under a microscope at a wavelength of 470 nm.

Chemical Properties

Molecular Weight	376.27
Formula	C₂₀H₁₀Na₂O₅
Cas No.	518-47-8
Smiles	[Na+].[Na+].[O-]C(=O)c1ccccc1-c1c2ccc([O-])cc2oc2cc(=O)ccc12
Relative Density.	0.579 g/cm3. Temperature:29.6 °C.;0.779 g/cm3. Temperature:29.6 °C.

Storage & Solubility Information

Storage

Keep away from direct sunlight Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 3.77 mg/mL (10.02 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6577 mL	13.2883 mL	26.5767 mL	132.8833 mL
5 mM	0.5315 mL	2.6577 mL	5.3153 mL	26.5767 mL
10 mM	0.2658 mL	1.3288 mL	2.6577 mL	13.2883 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc