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DL-Goitrin

🥰Excellent
Catalog No. T2S1778Cas No. 13190-34-6

DL-Goitrin is a potent antithyroid compound found naturally in crucifers. DL-Goitrin is responsible for the induction of glutathione S-transferases. DL-Goitrin is a moderate inhibitor of purified bovine adrenal dopamine beta-hydroxylase, leads to a depression of brain norepinephrine and to an elevation of heart and adrenal dopamine.

DL-Goitrin
Other Forms of DL-Goitrin:

DL-Goitrin

🥰Excellent
Purity: 99.94%
Catalog No. T2S1778Cas No. 13190-34-6
DL-Goitrin is a potent antithyroid compound found naturally in crucifers. DL-Goitrin is responsible for the induction of glutathione S-transferases. DL-Goitrin is a moderate inhibitor of purified bovine adrenal dopamine beta-hydroxylase, leads to a depression of brain norepinephrine and to an elevation of heart and adrenal dopamine.
Pack SizePriceAvailabilityQuantity
5 mg$59In Stock
10 mg$97In Stock
25 mg$163In Stock
50 mg$243In Stock
100 mg$359In Stock
1 mL x 10 mM (in DMSO)$54In Stock
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Purity:99.94%
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COA HNMR HPLC

Product Introduction

Bioactivity
Description
DL-Goitrin is a potent antithyroid compound found naturally in crucifers. DL-Goitrin is responsible for the induction of glutathione S-transferases. DL-Goitrin is a moderate inhibitor of purified bovine adrenal dopamine beta-hydroxylase, leads to a depression of brain norepinephrine and to an elevation of heart and adrenal dopamine.
Chemical Properties
Molecular Weight129.18
FormulaC5H7NOS
Cas No.13190-34-6
SmilesC(=C)C1OC(=S)NC1
Relative Density.1.19 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (387.06 mM), Sonication is recommended.
Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM7.7411 mL38.7057 mL77.4114 mL387.0568 mL
5 mM1.5482 mL7.7411 mL15.4823 mL77.4114 mL
10 mM0.7741 mL3.8706 mL7.7411 mL38.7057 mL
20 mM0.3871 mL1.9353 mL3.8706 mL19.3528 mL
50 mM0.1548 mL0.7741 mL1.5482 mL7.7411 mL
100 mM0.0774 mL0.3871 mL0.7741 mL3.8706 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

DL-GoitrinDLGoitrinDL Goitrinbovine adrenal dopamine beta-hydroxylase
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