Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ac-Exatecan, the acetylated form of Exatecan (DX-8951), serves as a prevalent cytotoxic agent in antibody-drug conjugate (ADC) formulations (ADC Cytotoxin) and acts as an inhibitor of DNA topoisomerase I with an IC50 value of 2.2 μM [1].
Description | Ac-Exatecan, the acetylated form of Exatecan (DX-8951), serves as a prevalent cytotoxic agent in antibody-drug conjugate (ADC) formulations (ADC Cytotoxin) and acts as an inhibitor of DNA topoisomerase I with an IC50 value of 2.2 μM [1]. |
Molecular Weight | 477.48 |
Formula | C26H24FN3O5 |
CAS No. | 2922852-48-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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Ac-Exatecan 2922852-48-8 DNA Damage/DNA Repair Topoisomerase inhibitor inhibit