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Methylnaltrexone bromide

Name: Methylnaltrexone bromide
Brand: TargetMol
SKU: T21422
Price: 47 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T21422Cas No. 73232-52-7

Alias Relistor, MOA-728, MOA728, MOA 728, Methylnaltrexone

Methylnaltrexone bromide (MOA-728) is one of the newer agents of peripherally-acting μ-opioid antagonists. Methylnaltrexone bromide acts to reverse some of the side effects of opioid drugs such as constipation without affecting analgesia or precipitating withdrawals.

Methylnaltrexone bromide

🥰Excellent

Purity: 99.02%

Catalog No. T21422Alias Relistor, MOA-728, MOA728, MOA 728, MethylnaltrexoneCas No. 73232-52-7

Pack Size	Price	Availability
2 mg	$47	In Stock
5 mg	$77	In Stock
10 mg	$118	In Stock
25 mg	$200	In Stock
50 mg	$286	In Stock
100 mg	$497	In Stock
1 mL x 10 mM (in DMSO)	$91	In Stock

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Batch Information

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Purity:99.02%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Methylnaltrexone bromide (MOA-728) is one of the newer agents of peripherally-acting μ-opioid antagonists. Methylnaltrexone bromide acts to reverse some of the side effects of opioid drugs such as constipation without affecting analgesia or precipitating withdrawals.
Synonyms	Relistor, MOA-728, MOA728, MOA 728, Methylnaltrexone

Chemical Properties

Molecular Weight	436.35
Formula	C₂₁H₂₆BrNO₄
Cas No.	73232-52-7
Smiles	O=C1[C@@](OC2=C(O)C=CC3=C24)([H])[C@@]54CC[N+](C)(CC6CC6)[C@@](C3)([H])[C@]5(O)CC1.[Br-]
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: Insoluble

DMSO: 60 mg/mL (137.5 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2917 mL	11.4587 mL	22.9174 mL	114.5869 mL
5 mM	0.4583 mL	2.2917 mL	4.5835 mL	22.9174 mL
10 mM	0.2292 mL	1.1459 mL	2.2917 mL	11.4587 mL
20 mM	0.1146 mL	0.5729 mL	1.1459 mL	5.7293 mL
50 mM	0.0458 mL	0.2292 mL	0.4583 mL	2.2917 mL
100 mM	0.0229 mL	0.1146 mL	0.2292 mL	1.1459 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc