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A2AAR/HDAC-IN-2

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Catalog No. T62717Cas No. 2767560-94-9

A2AAR/HDAC-IN-2 is a potent dual A2AAR/HDAC inhibitor with good affinity for A2AAR (Ki: 10.3 nM) and effective HDAC1 inhibition (IC50: 18.5 nM). A2AAR/HDAC-IN-2 is applicable in anti-tumour studies.

A2AAR/HDAC-IN-2

A2AAR/HDAC-IN-2

😃Good
Catalog No. T62717Cas No. 2767560-94-9
A2AAR/HDAC-IN-2 is a potent dual A2AAR/HDAC inhibitor with good affinity for A2AAR (Ki: 10.3 nM) and effective HDAC1 inhibition (IC50: 18.5 nM). A2AAR/HDAC-IN-2 is applicable in anti-tumour studies.
Pack SizePriceAvailabilityQuantity
25 mg$1,520 6-8 weeks
50 mg$1,980 6-8 weeks
100 mg$2,500 6-8 weeks
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Product Introduction

Bioactivity
Description
A2AAR/HDAC-IN-2 is a potent dual A2AAR/HDAC inhibitor with good affinity for A2AAR (Ki: 10.3 nM) and effective HDAC1 inhibition (IC50: 18.5 nM). A2AAR/HDAC-IN-2 is applicable in anti-tumour studies.
Targets&IC50
A2AAR:10.3 nM (Ki), HDAC8:1408.9 nM, HDAC2:16.0 nM, HDAC6:2.1 nM, A3AR:＞10 μM, A2BAR:513.0 nM (Ki), A1AR:105.6 nM (Ki), HDAC1:18.5 nM, HDAC3:13.6 nM
Chemical Properties
Molecular Weight450.49
FormulaC23H26N6O4
Cas No.2767560-94-9
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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