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Isomerazin

Name: Isomerazin
Brand: TargetMol
SKU: TN1786
Price: 98 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN1786Cas No. 1088-17-1

Alias Isomeranzin

Isomerazin (Isomeranzin) has anti-inflammatory activity, it suppresses inflammation by inhibiting M1 macrophage polarization through the p65, NF-κB and ERK pathway.

Isomerazin

🥰Excellent

Purity: 99.8%

Catalog No. TN1786Alias IsomeranzinCas No. 1088-17-1

Isomerazin (Isomeranzin) has anti-inflammatory activity, it suppresses inflammation by inhibiting M1 macrophage polarization through the p65, NF-κB and ERK pathway.

Pack Size	Price	Availability
1 mg	$98	In Stock
5 mg	$263	In Stock
10 mg	$388	In Stock
25 mg	$639	In Stock
50 mg	$898	In Stock
1 mL x 10 mM (in DMSO)	$238	In Stock

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Batch Information

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Purity:99.8%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	Isomerazin (Isomeranzin) has anti-inflammatory activity, it suppresses inflammation by inhibiting M1 macrophage polarization through the p65, NF-κB and ERK pathway.
Synonyms	Isomeranzin

Chemical Properties

Molecular Weight	260.29
Formula	C₁₅H₁₆O₄
Cas No.	1088-17-1
Smiles	COc1ccc2ccc(=O)oc2c1CC(=O)C(C)C
Relative Density.	1.178 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (230.51 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.8419 mL	19.2093 mL	38.4187 mL	192.0934 mL
5 mM	0.7684 mL	3.8419 mL	7.6837 mL	38.4187 mL
10 mM	0.3842 mL	1.9209 mL	3.8419 mL	19.2093 mL
20 mM	0.1921 mL	0.9605 mL	1.9209 mL	9.6047 mL
50 mM	0.0768 mL	0.3842 mL	0.7684 mL	3.8419 mL
100 mM	0.0384 mL	0.1921 mL	0.3842 mL	1.9209 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc