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Anti-Mouse CD3ε Antibody (KT3) is an inhibitory antibody derived from rats, targeting mouse CD3ε, which can promote thymocyte proliferation and is suitable for immunology-related research.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $99 | 2-4 weeks | 2-4 weeks | |
| 5 mg | $356 | 2-4 weeks | 2-4 weeks | |
| 10 mg | $589 | 2-4 weeks | 2-4 weeks |
| Description | Anti-Mouse CD3ε Antibody (KT3) is an inhibitory antibody derived from rats, targeting mouse CD3ε, which can promote thymocyte proliferation and is suitable for immunology-related research. |
| In vitro | After 72 hours of treatment with Anti-Mouse CD3ε Antibody (KT3), it can enhance the proliferation process triggered by T cell receptors in thymocytes[1]. When Anti-Mouse CD3ε Antibody (KT3) acts at a concentration of 1 μg/mL for 30 minutes, it will cause impairment of calcium ion flux in thymocytes and mature lymph node T cells[2]. |
| In vivo | Anti-Mouse CD3ε Antibody (KT3) administered intravenously at a dose of 10 μg can induce preferential death of mouse γδ T cells and promote their expression of Fas-L[3]. |
| Clone | KT3 |
| Reactivity | Mouse |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | CD3e |
| Molecular Weight | 150 kDa |
| Isotype | Rat IgG2a |
| Recommended Isotype Control |
| Storage | store at low temperature | store at -20°C | Shipping with blue ice. |
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