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Anti-Mouse CD3ε Antibody (KT3)

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Catalog No. T9901A-593 Copy Product Info
Purity: 95%
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Anti-Mouse CD3ε Antibody (KT3) is an inhibitory antibody derived from rats, targeting mouse CD3ε, which can promote thymocyte proliferation and is suitable for immunology-related research.

Anti-Mouse CD3ε Antibody
(KT3)

Pack SizePriceUSA StockGlobal StockQuantity
1 mg$99-In Stock
5 mg$3562-4 weeks2-4 weeks
10 mg$5892-4 weeks2-4 weeks
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:99.3% (SDS-PAGE); 99.8% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Anti-Mouse CD3ε Antibody (KT3) is an inhibitory antibody derived from rats, targeting mouse CD3ε, which can promote thymocyte proliferation and is suitable for immunology-related research.
In vitro
After 72 hours of treatment with Anti-Mouse CD3ε Antibody (KT3), it can enhance the proliferation process triggered by T cell receptors in thymocytes[1].
When Anti-Mouse CD3ε Antibody (KT3) acts at a concentration of 1 μg/mL for 30 minutes, it will cause impairment of calcium ion flux in thymocytes and mature lymph node T cells[2].
In vivo
Anti-Mouse CD3ε Antibody (KT3) administered intravenously at a dose of 10 μg can induce preferential death of mouse γδ T cells and promote their expression of Fas-L[3].
Clone
KT3
Reactivity
Mouse
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetCD3e
Chemical Properties
Molecular Weight143.66 kDa
Antibody Information
IsotypeRat IgG2a kappa
Recommended Isotype Control
Storage & Solubility Information
StorageStore at low temperature Store at -20°C Shipping with blue ice/Shipping at ambient temperature.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: Anti-Mouse CD3ε Antibody (KT3) in vivo | Anti-Mouse CD3ε Antibody (KT3) in vitro | Anti-Mouse CD3ε Antibody (KT3) molecular weight