Powder: -20°C for 3 years | In solvent: -80°C for 1 year
JB002, a myosin II inhibitor, exhibits potent activity with an IC50 of ≤10 μM. It holds potential for research applications in muscle spasticity, chronic musculoskeletal pain, and hypertrophic cardiomyopathy.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 70.00 | |
5 mg | In stock | $ 172.00 | |
10 mg | In stock | $ 278.00 | |
25 mg | In stock | $ 563.00 | |
50 mg | In stock | $ 786.00 | |
100 mg | In stock | $ 1,090.00 | |
500 mg | In stock | $ 2,180.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 189.00 |
Description | JB002, a myosin II inhibitor, exhibits potent activity with an IC50 of ≤10 μM. It holds potential for research applications in muscle spasticity, chronic musculoskeletal pain, and hypertrophic cardiomyopathy. |
Targets&IC50 | Myosin II:≤10 μM |
In vitro | JB002 exhibits excellent selectivity between cardiac and skeletal muscle myosin, but shows no detectable activity against non-muscle IIB.[1] |
Molecular Weight | 293.32 |
Formula | C18H15NO3 |
CAS No. | 30408-07-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 28.1 mg/mL (95.9 mM), Sonication and heating to 60℃ are recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
JB002 30408-07-2 Cytoskeletal Signaling Myosin JB 002 JB-002 inhibitor inhibit