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Neostigmine bromide

Name: Neostigmine bromide
Brand: TargetMol
SKU: T1624
Price: 33 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T1624Cas No. 114-80-7

Alias Neoserine bromide, Eustigmin bromide

Neostigmine bromide is a cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not cross the blood-brain barrier.

Neostigmine bromide

🥰Excellent

Purity: 98.39%

Catalog No. T1624Alias Neoserine bromide, Eustigmin bromideCas No. 114-80-7

Pack Size	Price	Availability	Quantity
50 mg	$33	In Stock
1 mL x 10 mM (in DMSO)	$53	In Stock

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This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:98.39%

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COA LCMS HNMR

Product Introduction

Bioactivity

Description	Neostigmine bromide is a cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not cross the blood-brain barrier.
Synonyms	Neoserine bromide, Eustigmin bromide

Chemical Properties

Molecular Weight	303.2
Formula	C₁₂H₁₉BrN₂O₂
Cas No.	114-80-7
Smiles	[Br-].CN(C)C(=O)Oc1cccc(c1)[N+](C)(C)C
Relative Density.	1.4344 g/cm3 (Estimated)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 38 mg/mL (125.33 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.2982 mL	16.4908 mL	32.9815 mL	164.9077 mL
5 mM	0.6596 mL	3.2982 mL	6.5963 mL	32.9815 mL
10 mM	0.3298 mL	1.6491 mL	3.2982 mL	16.4908 mL
20 mM	0.1649 mL	0.8245 mL	1.6491 mL	8.2454 mL
50 mM	0.0660 mL	0.3298 mL	0.6596 mL	3.2982 mL
100 mM	0.0330 mL	0.1649 mL	0.3298 mL	1.6491 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc