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Ondansetron hydrochloride

Name: Ondansetron hydrochloride
Brand: TargetMol
SKU: T6616
Price: 53 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T6616Cas No. 99614-01-4

Alias Zofran, SN 307, Ondansetron HCl, NSC 665799, GR 38032 HCl, Emeset

Ondansetron hydrochloride (Zofran) is a serotonin 5-HT3 receptor antagonist, used to prevent nausea and vomiting caused by cancer chemotherapy, and radiation therapy.

Ondansetron hydrochloride

🥰Excellent

Purity: 99.78%

Catalog No. T6616Alias Zofran, SN 307, Ondansetron HCl, NSC 665799, GR 38032 HCl, EmesetCas No. 99614-01-4

Ondansetron hydrochloride (Zofran) is a serotonin 5-HT3 receptor antagonist, used to prevent nausea and vomiting caused by cancer chemotherapy, and radiation therapy.

Pack Size	Price	Availability
25 mg	$37	In Stock
50 mg	$53	In Stock
100 mg	Preferential	In Stock
1 mL x 10 mM (in DMSO)	$39	In Stock

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Purity:99.78%

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COA HNMR HPLC LCMS

Product Introduction

Bioactivity

Description	Ondansetron hydrochloride (Zofran) is a serotonin 5-HT3 receptor antagonist, used to prevent nausea and vomiting caused by cancer chemotherapy, and radiation therapy.
Targets&IC50	5-HT3:103 pM, 5-HT:3.4 microM(EC50)
Synonyms	Zofran, SN 307, Ondansetron HCl, NSC 665799, GR 38032 HCl, Emeset

Chemical Properties

Molecular Weight	329.82
Formula	C₁₈H₁₉N₃O·HCl
Cas No.	99614-01-4
Smiles	Cl.CN1C2=CC=CC=C2C2=C1CCC(CN1C=CN=C1C)C2=O
Relative Density.	1.27g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 16.5 mg/mL (50.03 mM), Sonication is recommended.

DMSO: 60 mg/mL (181.92 mM), Sonication is recommended.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	3.0320 mL	15.1598 mL	30.3196 mL	151.5978 mL
5 mM	0.6064 mL	3.0320 mL	6.0639 mL	30.3196 mL
10 mM	0.3032 mL	1.5160 mL	3.0320 mL	15.1598 mL
20 mM	0.1516 mL	0.7580 mL	1.5160 mL	7.5799 mL
50 mM	0.0606 mL	0.3032 mL	0.6064 mL	3.0320 mL

DMSO

	1mg	5mg	10mg	50mg
100 mM	0.0303 mL	0.1516 mL	0.3032 mL	1.5160 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

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A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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