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Lalistat 2

Name: Lalistat 2
Brand: TargetMol
SKU: T41160
Price: 38 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T41160Cas No. 1234569-09-5

Lalistat 2 is a selective inhibitor of lysosomal acid lipase with IC50 of 152 nM and exhibits no inhibition of human pancreatic lipase or bovine milk lipoprotein lipase (up to 10 μM).

Lalistat 2

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Purity: 99.84%

Catalog No. T41160Cas No. 1234569-09-5

Lalistat 2 is a selective inhibitor of lysosomal acid lipase with IC50 of 152 nM and exhibits no inhibition of human pancreatic lipase or bovine milk lipoprotein lipase (up to 10 μM).

Pack Size	Price	Availability
1 mg	$38	In Stock
5 mg	$89	In Stock
10 mg	$139	In Stock
25 mg	$275	In Stock
50 mg	$513	In Stock
100 mg	$747	In Stock
500 mg	$1,560	Backorder
1 mL x 10 mM (in DMSO)	$97	In Stock

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Batch Information

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Purity:99.84%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description

Lalistat 2 is a selective inhibitor of lysosomal acid lipase with IC50 of 152 nM and exhibits no inhibition of human pancreatic lipase or bovine milk lipoprotein lipase (up to 10 μM).

Chemical Properties

Molecular Weight	296.39
Formula	C₁₃H₂₀N₄O₂S
Cas No.	1234569-09-5
Smiles	O=C(Oc1nsnc1N1CCCCC1)N1CCCCC1

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (168.7 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.3739 mL	16.8697 mL	33.7393 mL	168.6966 mL
5 mM	0.6748 mL	3.3739 mL	6.7479 mL	33.7393 mL
10 mM	0.3374 mL	1.6870 mL	3.3739 mL	16.8697 mL
20 mM	0.1687 mL	0.8435 mL	1.6870 mL	8.4348 mL
50 mM	0.0675 mL	0.3374 mL	0.6748 mL	3.3739 mL
100 mM	0.0337 mL	0.1687 mL	0.3374 mL	1.6870 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc