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DihydroarteMisinic acid

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Catalog No. THS1455Cas No. 85031-59-0
Alias Dihydro-Artmisinic Acid

DihydroarteMisinic acid (Dihydro-Artmisinic Acid) is a natural product from Artemisia annua and the main direct precursor of artemisinin, which is a medicinal herb that is widely used to treat Malaria.

DihydroarteMisinic acid

DihydroarteMisinic acid

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🥰Excellent
Purity: 99.17%
Catalog No. THS1455Alias Dihydro-Artmisinic AcidCas No. 85031-59-0
DihydroarteMisinic acid (Dihydro-Artmisinic Acid) is a natural product from Artemisia annua and the main direct precursor of artemisinin, which is a medicinal herb that is widely used to treat Malaria.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 mg$29In StockIn Stock
50 mgPreferentialIn StockIn Stock
1 mL x 10 mM (in DMSO)$29In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.17%
Appearance:Solid
Color:White
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Product Introduction

DihydroarteMisinic acid AI Summary
DihydroarteMisinic acid exhibits promising antimicrobial properties, demonstrating activity against Staphylococcus aureus JE2 with a minimum inhibitory concentration (MIC) of 100.0 μg/mL, Cryptococcus neoformans H99 with an MIC of 25.0 μg/mL, and Pseudomonas aeruginosa PA14 with an MIC greater than 100.0 μg/mL. These findings suggest significant potential for antibacterial and antifungal applications, given the observed reductions in microbial growth across multiple strains..
Note: Summary generated by AI. Data source: ChEMBL
Bioactivity
Description
DihydroarteMisinic acid (Dihydro-Artmisinic Acid) is a natural product from Artemisia annua and the main direct precursor of artemisinin, which is a medicinal herb that is widely used to treat Malaria.
SynonymsDihydro-Artmisinic Acid
Chemical Properties
Molecular Weight236.35
FormulaC15H24O2
Cas No.85031-59-0
Smiles[H][C@@]12CCC(C)=C[C@]1([H])[C@@H](CC[C@H]2C)[C@@H](C)C(O)=O
Relative Density.0.999 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble
DMSO: 43 mg/mL (181.93 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (8.46 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.2310 mL21.1551 mL42.3101 mL211.5507 mL
5 mM0.8462 mL4.2310 mL8.4620 mL42.3101 mL
10 mM0.4231 mL2.1155 mL4.2310 mL21.1551 mL
20 mM0.2116 mL1.0578 mL2.1155 mL10.5775 mL
50 mM0.0846 mL0.4231 mL0.8462 mL4.2310 mL
100 mM0.0423 mL0.2116 mL0.4231 mL2.1155 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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