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Caerulomycin A

Name: Caerulomycin A
Brand: TargetMol
SKU: T14854
Price: 148 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T14854Cas No. 21802-37-9

Alias Cerulomycin, Caerulomycin

Caerulomycin A (Caerulomycin) (Cerulomycin; Caerulomycin) is an antifungal compound. Which induces generation of T cells, enhances TGF-β-Smad3 protein signaling via suppressing interferon-γ-induced STAT1 signaling. Antifungal and antibiotic activity, and used in autoimmune diseases.

Caerulomycin A

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Purity: 99.28%

Catalog No. T14854Alias Cerulomycin, CaerulomycinCas No. 21802-37-9

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$148	In Stock	In Stock
5 mg	$298	In Stock	In Stock
10 mg	$447	In Stock	In Stock
25 mg	$768	In Stock	In Stock
50 mg	$1,120	In Stock	In Stock
100 mg	$1,480	In Stock	In Stock
200 mg	$1,960	-	In Stock
1 mL x 10 mM (in DMSO)	$275	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.28%

Appearance:Solid

Color:Yellow

Resource Download

COA HNMR LCMS

Product Introduction

Caerulomycin A AI Summary

Caerulomycin A exhibits antimicrobial activity against Candida albicans, Pseudomonas aeruginosa, and Escherichia coli with MIC values of 21800.0 nM for both Candida albicans and Pseudomonas aeruginosa, and 10900.0 nM for Escherichia coli. It also demonstrates antifungal activity against fluconazole-resistant Candida glabrata and Candida krusei with a MIC of 0.39 µg/mL, using the CLSI protocol via macrobroth dilution method. In addition, Caerulomycin A shows cytotoxicity against human KB cells with an IC50 greater than 50000.0 nM, against human A549 cells with an IC50 of 260.0 nM, and against human HL60 cells with an IC50 of 710.0 nM..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Caerulomycin A (Caerulomycin) (Cerulomycin; Caerulomycin) is an antifungal compound. Which induces generation of T cells, enhances TGF-β-Smad3 protein signaling via suppressing interferon-γ-induced STAT1 signaling. Antifungal and antibiotic activity, and used in autoimmune diseases.
Synonyms	Cerulomycin, Caerulomycin

Chemical Properties

Molecular Weight	229.23
Formula	C₁₂H₁₁N₃O₂
Cas No.	21802-37-9
Smiles	COc1cc(\C=N\O)nc(c1)-c1ccccn1
Relative Density.	1.23g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 150 mg/mL (654.36 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 4 mg/mL (17.45 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.3624 mL	21.8122 mL	43.6243 mL	218.1215 mL
5 mM	0.8725 mL	4.3624 mL	8.7249 mL	43.6243 mL
10 mM	0.4362 mL	2.1812 mL	4.3624 mL	21.8122 mL
20 mM	0.2181 mL	1.0906 mL	2.1812 mL	10.9061 mL
50 mM	0.0872 mL	0.4362 mL	0.8725 mL	4.3624 mL
100 mM	0.0436 mL	0.2181 mL	0.4362 mL	2.1812 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc