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Butylboronicacid

Catalog No. T77348 Copy Product Info
Purity: 99.96%
🥰Excellent
Butylboronicacid is a competitive inhibitor of urease and acts as a monosaccharide complexing reagent.

Butylboronicacid

Copy Product Info
🥰Excellent
Catalog No. T77348

Butylboronicacid is a competitive inhibitor of urease and acts as a monosaccharide complexing reagent.

Butylboronicacid
Cas No. 4426-47-5
Pack SizePriceUSA StockGlobal StockQuantity
1 g$29-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:99.96%
Appearance:Solid
Color:White
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Product Introduction

Butylboronicacid AI Summary
Butylboronicacid exhibits a range of inhibitory activities against different enzymes. It inhibits the subtilisin Carlsberg enzyme with a Ki value of 1,300,000 nM. The compound has been tested against Escherichia coli AmpC beta-lactamase, demonstrating a Ki value greater than 100,000 nM, implying weak or no inhibitory activity against this enzyme. Additionally, Butylboronicacid shows inhibitory activity against Haemophilus influenzae recombinant DapE with an IC50 value of approximately 10,000,000 nM and against AAP with a Ki value of 10,000 nM..
Note: Summary generated by AI. Data source: ChEMBL
Bioactivity
Description
Butylboronicacid is a competitive inhibitor of urease and acts as a monosaccharide complexing reagent.
Targets&IC50
Urease (soybean):2.00 +/- 0.11 mM(Ki)
Chemical Properties
Molecular Weight101.94
FormulaC4H11BO2
Cas No.4426-47-5
SmilesCCCCB(O)O
Storage & Solubility Information
StorageStore at low temperature | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (490.48 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM9.8097 mL49.0485 mL98.0969 mL490.4846 mL
5 mM1.9619 mL9.8097 mL19.6194 mL98.0969 mL
10 mM0.9810 mL4.9048 mL9.8097 mL49.0485 mL
20 mM0.4905 mL2.4524 mL4.9048 mL24.5242 mL
50 mM0.1962 mL0.9810 mL1.9619 mL9.8097 mL
100 mM0.0981 mL0.4905 mL0.9810 mL4.9048 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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