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SRX3177

Catalog No. T69742 CAS 2241237-51-2

SRX3177 is a novel and potent inhibitor of BRD4, PI3K and CDK.SRX3177 has potential anticancer activity.

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SRX3177, CAS 2241237-51-2

Pack Size	Availability	Price/USD
1 mg	In stock	$ 148.00
5 mg	In stock	$ 372.00
10 mg	In stock	$ 597.00
25 mg	In stock	$ 935.00
50 mg	In stock	$ 1,260.00
100 mg	In stock	$ 1,690.00
1 mL * 10 mM (in DMSO)	In stock	$ 480.00

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Purity: 99.16%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

SRX3177 is a novel and potent inhibitor of BRD4, PI3K and CDK.SRX3177 has potential anticancer activity.

Molecular Weight	584.69
Formula	C31H32N6O4S
CAS No.	2241237-51-2

Storage

store at low temperature,keep away from direct sunlight

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 20 mg/mL (34.21 mM), Sonication is recommended.

References and Literature

1. Burgoyne AM, et al. A triple action CDK4/6-PI3K-BET inhibitor with augmented cancer cell cytotoxicity. Cell Discov. 2020 Jul 28;6(1):49.

Related compound libraries

This product is contained In the following compound libraries：

Inhibitor Library Kinase Inhibitor Library

Related Products

Related compounds with same targets

PROTAC BRD4 ligand-1 (S,R)-CFT8634 BRM/BRG1 ATP Inhibitor-1 EML 425 GNE-064 MZ 1 ZL0420 UNC1215

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

SRX3177 2241237-51-2 Cell Cycle/Checkpoint Chromatin/Epigenetic PI3K/Akt/mTOR signaling CDK PI3K Epigenetic Reader Domain MEDS 433 SRX-3177 MEDS-433 SRX 3177 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.