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MS8511 hydrochloride

Name: MS8511 hydrochloride
Brand: TargetMol
SKU: T204198
Price: 166 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T204198Cas No. 3031788-28-7

Alias MS-8511 hydrochloride, MS-8511 HCl, MS8511 HCl

MS8511 hydrochloride is a selective G9a/GLP inhibitor with IC50 values of 100 nM and 140 nM respectively, exhibiting covalent and irreversible characteristics. MS8511 reduces intracellular H3K9me2 levels and enhances anti-proliferative activity, making it suitable for investigating multiple cancers.

MS8511 hydrochloride

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Purity: 99.24%

Catalog No. T204198Alias MS-8511 hydrochloride, MS-8511 HCl, MS8511 HClCas No. 3031788-28-7

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 mg	$166	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.24%

Color:White

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	MS8511 hydrochloride is a selective G9a/GLP inhibitor with IC50 values of 100 nM and 140 nM respectively, exhibiting covalent and irreversible characteristics. MS8511 reduces intracellular H3K9me2 levels and enhances anti-proliferative activity, making it suitable for investigating multiple cancers.
Synonyms	MS-8511 hydrochloride, MS-8511 HCl, MS8511 HCl

Chemical Properties

Molecular Weight	532.12
Formula	C₂₈H₄₂ClN₅O₃
Cas No.	3031788-28-7
Smiles	Cl.O=C(C=C)NC=1N=C2C=C(OCCCN3CCCC3)C(OC)=CC2=C(C1)NC4CCN(CC4)C(C)C

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Methanol: 24 mg/mL (45.1 mM), Sonication is recommended.

Solution Preparation Table

Methanol

	1mg	5mg	10mg	50mg
1 mM	1.8793 mL	9.3964 mL	18.7928 mL	93.9638 mL
5 mM	0.3759 mL	1.8793 mL	3.7586 mL	18.7928 mL
10 mM	0.1879 mL	0.9396 mL	1.8793 mL	9.3964 mL
20 mM	0.0940 mL	0.4698 mL	0.9396 mL	4.6982 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc