Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Thalidomide-5-methyl is the Thalidomide-based cereblon (CRBN) ligand. Thalidomide-5-methyl is used in the recruitment of CRBN protein.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 195.00 | |
5 mg | In stock | $ 437.00 | |
10 mg | In stock | $ 646.00 | |
25 mg | In stock | $ 987.00 | |
50 mg | In stock | $ 1,380.00 | |
100 mg | In stock | $ 1,860.00 | |
500 mg | In stock | $ 3,720.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 398.00 |
Description | Thalidomide-5-methyl is the Thalidomide-based cereblon (CRBN) ligand. Thalidomide-5-methyl is used in the recruitment of CRBN protein. |
In vitro | PROTACs contain two different ligands connected by a linker; one of them is a ligand for an E3 ubiquitin ligase and the other one is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1]. |
Molecular Weight | 272.26 |
Formula | C14H12N2O4 |
CAS No. | 40313-92-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (183.65 mM)
You can also refer to dose conversion for different animals. More
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Thalidomide-5-methyl 40313-92-6 PROTAC Ligand for E3 Ligase Thalidomide 5 methyl inhibit E3 ligase-recruiting Moiety Thalidomide5methyl Ligands for E3 Ligase Inhibitor inhibitor