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Cedazuridine

🥰Excellent
Catalog No. T26972Cas No. 1141397-80-9
Alias (4R)-2'-Deoxy-2',2'-difluoro-3,4,5,6-tetrahydrouridine

Cedazuridine ((4R)-2'-Deoxy-2',2'-difluoro-3,4,5,6-tetrahydrouridine) is an oral inhibitor of cytidine deaminase with antineoplastic properties.

Cedazuridine
Other Forms of Cedazuridine:
Cedazuridine hydrochlorideT60708
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Cedazuridine

🥰Excellent
Purity: 99.66%
Catalog No. T26972Alias (4R)-2'-Deoxy-2',2'-difluoro-3,4,5,6-tetrahydrouridineCas No. 1141397-80-9
Cedazuridine ((4R)-2'-Deoxy-2',2'-difluoro-3,4,5,6-tetrahydrouridine) is an oral inhibitor of cytidine deaminase with antineoplastic properties.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$50In StockIn Stock
5 mg$97In StockIn Stock
10 mg$155In StockIn Stock
25 mg$318In StockIn Stock
50 mg$479-In Stock
1 mL x 10 mM (in DMSO)$119In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.66%
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COA HNMR LCMS

Product Introduction

Bioactivity
Description
Cedazuridine ((4R)-2'-Deoxy-2',2'-difluoro-3,4,5,6-tetrahydrouridine) is an oral inhibitor of cytidine deaminase with antineoplastic properties.
In vivo
Oral Cedazuridine when combined with Azacitidine achieves successful tumor regression in both human cell line-derived xenograft transplantation experiment and patient-derived xenograft models[2].
Synonyms(4R)-2'-Deoxy-2',2'-difluoro-3,4,5,6-tetrahydrouridine
Chemical Properties
Molecular Weight268.21
FormulaC9H14F2N2O5
Cas No.1141397-80-9
SmilesOC[C@H]1O[C@@H](N2CC[C@@H](O)NC2=O)C(F)(F)[C@@H]1O
Relative Density.no data available
Storage & Solubility Information
Storagestore at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (186.42 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.7284 mL18.6421 mL37.2842 mL186.4211 mL
5 mM0.7457 mL3.7284 mL7.4568 mL37.2842 mL
10 mM0.3728 mL1.8642 mL3.7284 mL18.6421 mL
20 mM0.1864 mL0.9321 mL1.8642 mL9.3211 mL
50 mM0.0746 mL0.3728 mL0.7457 mL3.7284 mL
100 mM0.0373 mL0.1864 mL0.3728 mL1.8642 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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%
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

DNAMethyltransferaseDNA MethyltransferaseCytidine deaminaseCedazuridine2'-Deoxy-2',2'-difluoro-3,4,5,6-tetrahydrouridine
Related Tags: buy Cedazuridine | purchase Cedazuridine | Cedazuridine cost | order Cedazuridine | Cedazuridine chemical structure | Cedazuridine in vivo | Cedazuridine formula | Cedazuridine molecular weight
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