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Acriflavine Hydrochloride

Name: Acriflavine Hydrochloride
Brand: TargetMol
SKU: T19832
Price: 41 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T19832Cas No. 8063-24-9

Alias Acriflavine HCl

Acriflavine Hydrochloride (Acriflavine HCl) is a HIF-1α inhibitor. It acts by targeting HIF-1α-mediated pathways and decreasing the level of PGK1, VEGF, and HIF-1α in vitro and in vivo.

Acriflavine Hydrochloride

🥰Excellent

Purity: 99.8%

Catalog No. T19832Alias Acriflavine HClCas No. 8063-24-9

Acriflavine Hydrochloride (Acriflavine HCl) is a HIF-1α inhibitor. It acts by targeting HIF-1α-mediated pathways and decreasing the level of PGK1, VEGF, and HIF-1α in vitro and in vivo.

Pack Size	Price	Availability	Quantity
500 mg	$41	In Stock
1 mL x 10 mM (in DMSO)	$45	In Stock

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Batch Information

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Purity:99.8%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Acriflavine Hydrochloride (Acriflavine HCl) is a HIF-1α inhibitor. It acts by targeting HIF-1α-mediated pathways and decreasing the level of PGK1, VEGF, and HIF-1α in vitro and in vivo.
Synonyms	Acriflavine HCl

Chemical Properties

Molecular Weight	259.73
Formula	C₁₄H₁₄ClN₃
Cas No.	8063-24-9
Smiles	C[N+]1=C2C=C(N)C=CC2=CC3=C1C=C(N)C=C3.[Cl-]
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 30 mg/mL (115.5 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.8502 mL	19.2508 mL	38.5015 mL	192.5076 mL
5 mM	0.7700 mL	3.8502 mL	7.7003 mL	38.5015 mL
10 mM	0.3850 mL	1.9251 mL	3.8502 mL	19.2508 mL
20 mM	0.1925 mL	0.9625 mL	1.9251 mL	9.6254 mL
50 mM	0.0770 mL	0.3850 mL	0.7700 mL	3.8502 mL
100 mM	0.0385 mL	0.1925 mL	0.3850 mL	1.9251 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc