Shopping Cart

Remove All
Your shopping cart is currently empty

NAG-thiazoline

Name: NAG-thiazoline
Brand: TargetMol
SKU: T9190
Price: 47 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T9190Cas No. 179030-22-9

Alias GlcNAc-thiazoline

NAG-thiazoline (GlcNAc-thiazoline) is an O-GlcNAcase inhibitor with Ki value of 180 nM. It is active against V. campbellii with MIC value of 0.5 μM.

NAG-thiazoline

🥰Excellent

Purity: 99.35%

Catalog No. T9190Alias GlcNAc-thiazolineCas No. 179030-22-9

NAG-thiazoline (GlcNAc-thiazoline) is an O-GlcNAcase inhibitor with Ki value of 180 nM. It is active against V. campbellii with MIC value of 0.5 μM.

Pack Size	Price	Availability
5 mg	$47	In Stock
10 mg	$89	In Stock
25 mg	$189	In Stock
50 mg	$278	In Stock
100 mg	$452	In Stock
1 mL x 10 mM (in DMSO)	$50	In Stock

Add to Cart

Add to Quotation

Bulk & Custom

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:99.35%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	NAG-thiazoline (GlcNAc-thiazoline) is an O-GlcNAcase inhibitor with Ki value of 180 nM. It is active against V. campbellii with MIC value of 0.5 μM.
Targets&IC50	VhGlcNAcase:11.9 ± 1.0 μm
In vitro	NGT completely inhibited the growth of V. campbellii strain 650 with an minimal inhibitory concentration value of 0.5 μm[1].
Synonyms	GlcNAc-thiazoline

Chemical Properties

Molecular Weight	219.26
Formula	C₈H₁₃NO₄S
Cas No.	179030-22-9
Smiles	O[C@@H]1[C@@]2([C@](O[C@H](CO)[C@H]1O)(SC(C)=N2)[H])[H]
Relative Density.	1.81 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (250.84 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (9.12 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.5608 mL	22.8040 mL	45.6080 mL	228.0398 mL
5 mM	0.9122 mL	4.5608 mL	9.1216 mL	45.6080 mL
10 mM	0.4561 mL	2.2804 mL	4.5608 mL	22.8040 mL
20 mM	0.2280 mL	1.1402 mL	2.2804 mL	11.4020 mL
50 mM	0.0912 mL	0.4561 mL	0.9122 mL	4.5608 mL
100 mM	0.0456 mL	0.2280 mL	0.4561 mL	2.2804 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc