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Chlorindanol

Name: Chlorindanol
Brand: TargetMol
SKU: T1253
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T1253Cas No. 145-94-8

Alias Lanesta, Clorindanol, 7-Chloro-4-indanol

Chlorindanol (Lanesta) is a new antiseptic agent. It is nonallergenic and appears to be suitable for use as a topical antiseptic or sanitizer.

Chlorindanol

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Purity: 98.07%

Catalog No. T1253Alias Lanesta, Clorindanol, 7-Chloro-4-indanolCas No. 145-94-8

Chlorindanol (Lanesta) is a new antiseptic agent. It is nonallergenic and appears to be suitable for use as a topical antiseptic or sanitizer.

Pack Size	Price	USA Warehouse	Global Warehouse
200 mg	$31	-	In Stock
500 mg	$62	-	In Stock
1 g	$90	-	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:98.07%

Appearance:Solid

Color:White

Resource Download

COA HNMR HPLC

Product Introduction

Chlorindanol AI Summary

Chlorindanol exhibits a range of bioactivities, including notable antiviral and enzyme inhibitory properties. It functions as an inhibitor of ROR gamma transcriptional activity with a potency of 11220.2 nM. In Schwann cell assays, it shows activity with potencies of 36125.4 nM and 32196.8 nM in the PMP22 intronic element firefly luciferase assay and Schwann cell viability assay, respectively. Additionally, Chlorindanol demonstrates antiviral activity against SARS-CoV-2, inhibiting the virus-induced cytotoxicity in Caco-2 cells and VERO-6 cells at a concentration of 10 µM, though with relatively low inhibition rates of -1.71% and 0.06% respectively. Furthermore, it inhibits the SARS-CoV-2 3CL-Pro protease at 20 µM with an inhibition percentage of 8.095%. Finally, the compound shows inhibitory activity against the human HDAC6 enzyme, exhibiting 7.61% inhibition with a custom peptide substrate and -29.99% inhibition with a commercial peptide substrate..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Chlorindanol (Lanesta) is a new antiseptic agent. It is nonallergenic and appears to be suitable for use as a topical antiseptic or sanitizer.
Synonyms	Lanesta, Clorindanol, 7-Chloro-4-indanol

Chemical Properties

Molecular Weight	168.62
Formula	C₉H₉ClO
Cas No.	145-94-8
Smiles	Oc1ccc(Cl)c2CCCc12
Relative Density.	1.308g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (296.52 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (11.86 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.9305 mL	29.6525 mL	59.3049 mL	296.5247 mL
5 mM	1.1861 mL	5.9305 mL	11.8610 mL	59.3049 mL
10 mM	0.5930 mL	2.9652 mL	5.9305 mL	29.6525 mL
20 mM	0.2965 mL	1.4826 mL	2.9652 mL	14.8262 mL
50 mM	0.1186 mL	0.5930 mL	1.1861 mL	5.9305 mL
100 mM	0.0593 mL	0.2965 mL	0.5930 mL	2.9652 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc