Crisaborole-d4

Name: Crisaborole-d4
Brand: TargetMol
SKU: TMIJ-0249
Rating: 4.5 (1 reviews)

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Catalog No. TMIJ-0249

Alias PF06930164-d4, PF-06930164-d4, AN2728-d4, AN-2728-d4

Crisaborole-d4 (AN-2728-d4) is a 2H-labeled version of Crisaborole. Crisaborole is a phosphodiesterase 4 (PDE4) inhibitor and cytokine release inhibitor, used in the study of atopic dermatitis.

Crisaborole-d4

😃Good

Catalog No. TMIJ-0249Alias PF06930164-d4, PF-06930164-d4, AN2728-d4, AN-2728-d4

Crisaborole-d4 (AN-2728-d4) is a 2H-labeled version of Crisaborole. Crisaborole is a phosphodiesterase 4 (PDE4) inhibitor and cytokine release inhibitor, used in the study of atopic dermatitis.

Pack Size	Price	Availability	Quantity
1 mg	Inquiry	20 days
5 mg	Inquiry	20 days

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description	Crisaborole-d4 (AN-2728-d4) is a 2H-labeled version of Crisaborole. Crisaborole is a phosphodiesterase 4 (PDE4) inhibitor and cytokine release inhibitor, used in the study of atopic dermatitis.
Synonyms	PF06930164-d4, PF-06930164-d4, AN2728-d4, AN-2728-d4

Chemical Properties

Molecular Weight	255.07
Formula	C₁₄H₆D₄BNO₃
Smiles	C1(C#N)C([2H])=C([2H])C(OC2C=CC3B(O)OCC=3C=2)=C([2H])C=1[2H]
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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