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Suxibuzone

Name: Suxibuzone
Brand: TargetMol
SKU: T0319
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T0319Cas No. 27470-51-5

Alias Suxibuzonum, Suxibuzona, Calibene

Suxibuzone (Suxibuzona) is a drug used for joint and muscular pain. It is a prodrug of the non steroidal anti inflammatory drug phenylbutazone, and is commonly used in horses.

Suxibuzone

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Purity: 99.85%

Catalog No. T0319Alias Suxibuzonum, Suxibuzona, CalibeneCas No. 27470-51-5

Suxibuzone (Suxibuzona) is a drug used for joint and muscular pain. It is a prodrug of the non steroidal anti inflammatory drug phenylbutazone, and is commonly used in horses.

Pack Size	Price	Availability
5 mg	$30	In Stock
10 mg	$47	In Stock
25 mg	$76	In Stock
50 mg	$112	In Stock
100 mg	$165	In Stock
1 mL x 10 mM (in DMSO)	$52	In Stock

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Batch Information

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Purity:99.85%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Suxibuzone (Suxibuzona) is a drug used for joint and muscular pain. It is a prodrug of the non steroidal anti inflammatory drug phenylbutazone, and is commonly used in horses.
Synonyms	Suxibuzonum, Suxibuzona, Calibene

Chemical Properties

Molecular Weight	438.47
Formula	C₂₄H₂₆N₂O₆
Cas No.	27470-51-5
Smiles	CCCCC1(COC(=O)CCC(O)=O)C(=O)N(N(C1=O)c1ccccc1)c1ccccc1
Relative Density.	1.265g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (136.84 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (4.56 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2807 mL	11.4033 mL	22.8066 mL	114.0329 mL
5 mM	0.4561 mL	2.2807 mL	4.5613 mL	22.8066 mL
10 mM	0.2281 mL	1.1403 mL	2.2807 mL	11.4033 mL
20 mM	0.1140 mL	0.5702 mL	1.1403 mL	5.7016 mL
50 mM	0.0456 mL	0.2281 mL	0.4561 mL	2.2807 mL
100 mM	0.0228 mL	0.1140 mL	0.2281 mL	1.1403 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc