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Sulfacarbamide

Name: Sulfacarbamide
Brand: TargetMol
SKU: T0241
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T0241Cas No. 547-44-4

Alias Sulfanilylurea

Sulfacarbamide (Sulfanilylurea) is a blood sugar-lowering agent.

Sulfacarbamide

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Purity: 99.72%

Catalog No. T0241Alias SulfanilylureaCas No. 547-44-4

Sulfacarbamide (Sulfanilylurea) is a blood sugar-lowering agent.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
50 mg	$30	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.72%

Color:White

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Product Introduction

Sulfacarbamide AI Summary

Sulfacarbamide exhibits multifaceted bioactivities and physicochemical properties. It has been identified as an inhibitor of Escherichia coli Dihydropteroate synthase with an EII50 value of 8.4 and an in vitro inhibitor of E. coli growth with a GII50 value of 25000.0. The compound has a log P value of -1.1, indicating its hydrophilic nature. It also shows detrimental effects in terms of drug-induced liver injury (DILI), with a high severity index of 8.0 as noted in the DILI Prediction System (DILIps). Additionally, Sulfacarbamide exhibits antiviral activities, including inhibition of Lassa virus entry at 35481.3 nM potency and Ebola virus entry with AC50 values between 7079.5 nM and 8912.5 nM. Against SARS-CoV-2, it demonstrates variable inhibition rates and potencies, with an index of 0.3788 in Vero E6 cells, an inhibition rate of 8.23% in Caco-2 cells at 10 µM concentration, and a 13.66% inhibition of the SARS-CoV-2 3CL-Pro protease at 20 µM. The compound shows minimal inhibition of the human HDAC6 enzyme with a commercial substrate (1.5%) and negligible activity with a custom substrate (-14.65%). Furthermore, the compound's effectiveness across various bioactivities is generally limited, with AC50 values exceeding 30000.0 nM, indicating negligible effects on the tested targets..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Sulfacarbamide (Sulfanilylurea) is a blood sugar-lowering agent.
Synonyms	Sulfanilylurea

Chemical Properties

Molecular Weight	215.23
Formula	C₇H₉N₃O₃S
Cas No.	547-44-4
Smiles	NC(=O)NS(=O)(=O)c1ccc(N)cc1
Relative Density.	1.4565 g/cm3 (Estimated)

Storage & Solubility Information

Storage

store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 28 mg/mL (130.09 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.6462 mL	23.2310 mL	46.4619 mL	232.3096 mL
5 mM	0.9292 mL	4.6462 mL	9.2924 mL	46.4619 mL
10 mM	0.4646 mL	2.3231 mL	4.6462 mL	23.2310 mL
20 mM	0.2323 mL	1.1615 mL	2.3231 mL	11.6155 mL
50 mM	0.0929 mL	0.4646 mL	0.9292 mL	4.6462 mL
100 mM	0.0465 mL	0.2323 mL	0.4646 mL	2.3231 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc