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Cyromazine

Name: Cyromazine
Brand: TargetMol
SKU: T0845
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T0845Cas No. 66215-27-8

Alias Cyromazin, CGA-72662

Cyromazine (CGA-72662) is an ectoparasiticide. Insect growth regulator. Specific activity against dipterous larvae. Cyromazine is a fda approved for use in livestock.

Cyromazine

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Purity: 99.74%

Catalog No. T0845Alias Cyromazin, CGA-72662Cas No. 66215-27-8

Cyromazine (CGA-72662) is an ectoparasiticide. Insect growth regulator. Specific activity against dipterous larvae. Cyromazine is a fda approved for use in livestock.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 g	$29	-	In Stock
1 mL x 10 mM (in DMSO)	$50	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.74%

Appearance:Solid

Color:White

Resource Download

COA HNMR HPLC LCMS

Product Introduction

Bioactivity

Description	Cyromazine (CGA-72662) is an ectoparasiticide. Insect growth regulator. Specific activity against dipterous larvae. Cyromazine is a fda approved for use in livestock.
In vitro	In both plants and animals, Cyromazine undergoes dealkylation metabolism and, through environmental degradation, forms melamine.
In vivo	Cyromazine may act at certain stages of cuticle sclerotization, with little to no effect on dihydrofolate reductase and the activity of aminomethylphosphonic acid. It alters the percentage or total content of phenylalanine and tyrosine amino acids in the pupal exoskeleton cuticle, resulting in larvae exhibiting typical signs of Cyromazine intoxication. The mechanism of action likely involves inhibiting the synthesis of chitin and scleroprotein.
Synonyms	Cyromazin, CGA-72662

Chemical Properties

Molecular Weight	166.18
Formula	C₆H₁₀N₆
Cas No.	66215-27-8
Smiles	N(C=1N=C(N)N=C(N)N1)C2CC2
Relative Density.	1.622 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 1 mg/mL (6.02 mM), Sonication is recommended.

Ethanol: 2 mg/mL (12.04 mM), Sonication is recommended.

DMSO: 60 mg/mL (361.05 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 5 mg/mL (30.09 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

H2O/Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	6.0176 mL	30.0879 mL	60.1757 mL	300.8786 mL
5 mM	1.2035 mL	6.0176 mL	12.0351 mL	60.1757 mL

Ethanol/DMSO

	1mg	5mg	10mg	50mg
10 mM	0.6018 mL	3.0088 mL	6.0176 mL	30.0879 mL

DMSO

	1mg	5mg	10mg	50mg
20 mM	0.3009 mL	1.5044 mL	3.0088 mL	15.0439 mL
50 mM	0.1204 mL	0.6018 mL	1.2035 mL	6.0176 mL
100 mM	0.0602 mL	0.3009 mL	0.6018 mL	3.0088 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc