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MG 149

Name: MG 149
Brand: TargetMol
SKU: T6584
Price: 48 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T6584Cas No. 1243583-85-8

Alias Tip60 HAT inhibitor, MG149

MG 149 (Tip60 HAT inhibitor) is a selective and potent Tip60 inhibitor with IC50 of 74 uM, similar potentcy for MOF(IC50= 47 uM).

MG 149

🥰Excellent

Purity: 99.86%

Catalog No. T6584Alias Tip60 HAT inhibitor, MG149Cas No. 1243583-85-8

MG 149 (Tip60 HAT inhibitor) is a selective and potent Tip60 inhibitor with IC50 of 74 uM, similar potentcy for MOF(IC50= 47 uM).

Pack Size	Price	Availability
1 mg	$48	In Stock
2 mg	$68	In Stock
5 mg	$97	In Stock
10 mg	$179	In Stock
25 mg	$342	In Stock
50 mg	$546	In Stock
100 mg	$787	In Stock
1 mL x 10 mM (in DMSO)	$116	In Stock

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Batch Information

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Purity:99.86%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	MG 149 (Tip60 HAT inhibitor) is a selective and potent Tip60 inhibitor with IC50 of 74 uM, similar potentcy for MOF(IC50= 47 uM).
Targets&IC50	MOF:47 μM, Tip60:74 μM
Synonyms	Tip60 HAT inhibitor, MG149

Chemical Properties

Molecular Weight	340.46
Formula	C₂₂H₂₈O₃
Cas No.	1243583-85-8
Smiles	CCCCCCCc1ccc(CCc2cccc(O)c2C(O)=O)cc1
Relative Density.	1.100 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Ethanol: 63 mg/mL (185.04 mM), Sonication is recommended.

H2O: < 1 mg/mL (insoluble or slightly soluble)

DMSO: 50 mg/mL (146.86 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (5.87 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO/Ethanol

	1mg	5mg	10mg	50mg
1 mM	2.9372 mL	14.6860 mL	29.3720 mL	146.8601 mL
5 mM	0.5874 mL	2.9372 mL	5.8744 mL	29.3720 mL
10 mM	0.2937 mL	1.4686 mL	2.9372 mL	14.6860 mL
20 mM	0.1469 mL	0.7343 mL	1.4686 mL	7.3430 mL
50 mM	0.0587 mL	0.2937 mL	0.5874 mL	2.9372 mL
100 mM	0.0294 mL	0.1469 mL	0.2937 mL	1.4686 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc